[2-Fluoro-6-(morpholin-4-yl)pyridin-3-yl]boronic acid CAS 955374-17-1

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including [2-Fluoro-6-(morpholin-4-yl)pyridin-3-yl]boronic acid.

[2-Fluoro-6-(morpholin-4-yl)pyridin-3-yl]boronic acid (CAS 955374-17-1), molecular formula C9H12BFN2O3 and molecular weight 226.01 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of [2-Fluoro-6-(morpholin-4-yl)pyridin-3-yl]boronic acid (C9H12BFN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), [2-Fluoro-6-(morpholin-4-yl)pyridin-3-yl]boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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