Empagliflozin impurity 01 CAS 95574-97-3
| CAS No. | 95574-97-3 |
| Molecular Formula | C4H7ClO3 |
| Molecular Weight | 138.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Empagliflozin impurity 01 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Empagliflozin impurity 01 (CAS 95574-97-3, C4H7ClO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Empagliflozin impurity 01 is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 138.55 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H7ClO3 |
| Molecular Weight | 138.55 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 96 (CAS 106941-19-9)
- Empagliflozin impurity 158 (CAS 226213-72-5)
- Empagliflozin Impurity 82 (CAS 154006-52-7)
- Empagliflozin Impurity 159 (CAS 2820373-52-0)
- Empagliflozin Impurity 315 (CAS CATO-C4X-1065315)
- Empagliflozin impurity 323 (CAS CATO-C4X-1065323)
- Empagliflozin impurity 326 (CAS CATO-C4X-1065326)
- Empagliflozin Impurity 83(Mixture of Diastereomers) (CAS CATO-C4X-106583)
Recommended Standards
- 6-Cyano-3-chloropyridine (CAS 89809-64-3)
- Methyl (R)-3-chloro-2-hydroxypropanoate (CAS 82971-67-3)
- 6-Chloropyridine-2-carbonitrile (CAS 33252-29-8)
- Methyl 3-chloro-2-hydroxypropanoate (CAS 32777-04-1)
- Fospropofol Impurity 7 (CAS 250345-80-3)
- Orforglipron Impurity 111 (CAS CATO-C4X-3234111)
- Palbociclib Impurity 32 (CAS 1082876-26-3)
- Febantel-D6 (CAS 1173021-79-8)
- 5-Ethoxy-2-phenyloxazole-4-carbothioamide (CAS 128242-93-3)
- Thieno[2,3-c]pyridine-3-carboxylic acid (CAS 1337880-68-8)
- 1-(2-(3-Bromophenoxy)ethyl)-4-methylpiperidine (CAS 435283-23-1)
- 4-Amino-N,N-dipropylbenzenesulfonamide (CAS 21646-92-4)
- 2-(p-Tolyl)propanamide (CAS 127462-35-5)
- D-[Thr]5-Semaglutide (CAS CATO-C4X-2226245)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com