2-Ethynyl-1,4-difluorobenzene CAS 956386-38-2
| CAS No. | 956386-38-2 |
| Molecular Formula | C8H4F2 |
| Molecular Weight | 138.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Ethynyl-1,4-difluorobenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-Ethynyl-1,4-difluorobenzene (CAS 956386-38-2), a certified reference material (molecular formula C8H4F2, MW 138.11 g/mol) for analytical method development and quality control.
Owing to fluorine substitution, an aromatic ring system, 2-Ethynyl-1,4-difluorobenzene is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 138.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H4F2 |
| Molecular Weight | 138.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Ethynyl Standards
- 1-Ethynyl-2,3-difluorobenzene1-ethynyl-2,3-difluorobenzene (CAS 528878-43-5)
- 2-Ethynyl-1,3-difluorobenzene (CAS 381723-16-6)
- 4-Ethynyl-1-(2-fluoroethyl)-1H-pyrazole (CAS 1823843-56-6)
- 4-Ethynyl-5-fluoro-1,3-dimethyl-1H-pyrazole (CAS 1823967-57-2)
- 2-Ethynyl-5,8-dioxaspiro[3.4]octane (CAS 1392803-25-6)
- 6-Ethynyl-2-oxaspiro[3.3]heptan-6-ol (CAS 1884164-15-1)
- 1-Ethynyl-4-fluorobicyclo[2.2.1]heptane (CAS 2287310-81-8)
- 2-Ethynyl-6-fluorospiro[3.3]heptane (CAS 2715119-96-1)
Recommended Standards
- 3-(Difluoromethoxy)cyclobutan-1-ol (CAS 2007917-09-9)
- 3,3-Difluoro-1-(hydroxymethyl)cyclobutan-1-ol (CAS 2231674-33-0)
- [2,2-Difluoro-1-(hydroxymethyl)cyclopropyl]methanol (CAS 228580-15-2)
- Ethyl 2,2-Difluoropropionate (CAS 28781-85-3)
- 6-(3-Chlorophenyl)-2-hydroxy-4-(trifluoromethyl)nicotinonitrile (CAS 338749-71-6)
- Methyl n-(3-amino-2-methylphenyl)carbamate (CAS 157563-54-7)
- (2R)-2-(1,3-Dioxoisoindol-2-yl)-4-methylpentanoic acid (CAS 29588-87-2)
- 5,6-difluoro-1H-indole-3-carboxylic acid (CAS 959238-71-2)
- 2-Oxo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-6-carboxylic acid (CAS 1190318-74-1)
- (3-Bromo-5-(methoxymethyl)phenyl)boronic acid (CAS 2225179-17-7)
- 3-Hydroxy-3-(m-tolyl)propanenitrile (CAS 926210-85-7)
- (4S,4′S)-2,2′-(1,2-Phenylene)bis[4,5-dihydro-4-(1-methylpropyl)oxazole] (CAS 1004288-05-4)
- Erlotinib Impurity 101 (CAS CATO-C4X-1069101)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
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