N-Cbz-3-hydroxypyrrolidine CAS 95656-88-5

Purity 97%+In StockPharmaceutical Standards
CAS No.95656-88-5
Molecular FormulaC12H15NO3
Molecular Weight221.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-Cbz-3-hydroxypyrrolidine CAS 95656-88-5 chemical structure

Description

The occurrence of N-Cbz-3-hydroxypyrrolidine is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

N-Cbz-3-hydroxypyrrolidine (CAS 95656-88-5), molecular formula C12H15NO3 and molecular weight 221.25 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of N-Cbz-3-hydroxypyrrolidine (C12H15NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures N-Cbz-3-hydroxypyrrolidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H15NO3
Molecular Weight221.25 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Nitrogen Atoms1

Recommended Standards

Why CATO?