2-[2-(bromomethyl)-4-(trifluoromethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane CAS 957066-13-6
| CAS No. | 957066-13-6 |
| Molecular Formula | C14H23BBrF3O3 |
| Molecular Weight | 387.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-[2-(bromomethyl)-4-(trifluoromethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-[2-(bromomethyl)-4-(trifluoromethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 957066-13-6), molecular formula C14H23BBrF3O3 and molecular weight 387.04 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-[2-(bromomethyl)-4-(trifluoromethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (C14H23BBrF3O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H23BBrF3O3 |
| Molecular Weight | 387.04 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.5 |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
Related bromomethyl Standards
- 2-(Bromomethyl)-6-(difluoromethyl)-5-iodopyridine-3-acetonitrile (CAS 1804868-12-9)
- 2-(4-(Bromomethyl)-3-(difluoromethyl)-5-iodopyridin-2-yl)acetonitrile (CAS 1805432-36-3)
- 2-(Bromomethyl)-6-(difluoromethyl)-3-iodopyridine-5-acetonitrile (CAS 1805458-40-5)
- 2-(Bromomethyl)-6-(difluoromethyl)-3-iodopyridine-4-acetonitrile (CAS 1806022-96-7)
- Methyl 4-(Bromomethyl)-3,5-dibromobenzoate (CAS 444663-80-3)
- 2-(Bromomethyl)-4-(trifluoromethoxy)-6-(trifluoromethyl)pyridine-3-carbonyl chloride (CAS 1805241-91-1)
- 3-(4-(Bromomethyl)phenyl)-7-(diethylamino)-2H-chromen-2-one (CAS 177093-58-2)
- 2,7-Bis(bromomethyl)pyrene (CAS 63996-39-4)
Recommended Standards
- 2,4-Dibromo-6-[(1E)-{[(4-fluorophenyl)methyl]imino}methyl]phenol (CAS 477848-41-2)
- 6,8-dibromo-3-(4-fluorophenyl)-3,4-dihydro-2H-1,3-benzoxazine (CAS 478040-89-0)
- Stevensine (CAS 99102-22-4)
- 3-(2,5-Dibromobenzenesulfonamido)propanoic acid (CAS 554438-88-9)
- 6-Amino-5-hydroxynicotinic acid (CAS 1219026-99-9)
- 5-(Furan-2-yl)picolinonitrile (CAS 619334-50-8)
- 2-Hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione (CAS 5596-17-8)
- n-(4-Methylpiperidin-3-yl)isobutyramide (CAS 1341432-40-3)
- 6-Fluoro-1-methyl-1H-benzo[c][1,2]thiazin-4(3H)-one 2,2-dioxide (CAS 1708013-49-3)
- 2-(2-(Piperidin-4-yl)ethyl)isothiazolidine 1,1-dioxide (CAS 89151-54-2)
- Isavuconazole impurity 77 (CAS CATO-C4X-1236177)
- tert-Butyl (3-acetylthiophen-2-yl)carbamate (CAS 2005784-00-7)
- Methyl 1-amino-1H-benzo[d]imidazole-2-carboxylate (CAS 49628-57-1)
- Semaglutide impurity 107 (CAS CATO-C4X-2226107)
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