(3-Hydroxy-5-(trifluoromethoxy)phenyl)boronic acid CAS 957120-22-8
| CAS No. | 957120-22-8 |
| Molecular Formula | C7H6BF3O4 |
| Molecular Weight | 221.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(3-Hydroxy-5-(trifluoromethoxy)phenyl)boronic acid (CAS 957120-22-8) is a high-purity analytical reference standard with the molecular formula C7H6BF3O4 and a molecular weight of 221.93 g/mol.
(3-Hydroxy-5-(trifluoromethoxy)phenyl)boronic acid (C7H6BF3O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6BF3O4 |
| Molecular Weight | 221.93 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Hydroxy Standards
- (2-Hydroxy-4-(trifluoromethoxy)phenyl)boronic acid (CAS 1309768-22-6)
- (2-Hydroxy-5-(trifluoromethoxy)phenyl)boronic acid (CAS 1354819-26-3)
- 4-Hydroxy-2-(trifluoromethoxy)phenylboronic acid (CAS 2364439-35-8)
- (2-Hydroxy-6-(piperidin-2-yl)pyridin-4-yl)boronic acid (CAS 2256708-73-1)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4,5-dimethylfuran-2-yl)boronate (CAS 1073338-90-5)
- 4-Hydroxy-3-(trifluoromethoxy)benzoic acid (CAS 1093397-67-1)
- 2-Hydroxy-5-(trifluoromethoxy)benzoic acid (CAS 129644-57-1)
- 2-Hydroxy-3-(trifluoromethoxy)benzoic acid (CAS 773873-50-0)
Recommended Standards
- 2-(2,2,2-Trifluoroethoxy)pyrimidine-5-boronic acid (CAS 1401163-85-6)
- Holmium(III) fluoride,99.99% (CAS 13760-78-6)
- {[4-Fluoro-3-(trifluoromethyl)phenyl]methyl}boronic acid (CAS 1980905-33-6)
- 2-Fluoro-5-methyl-3-(trifluoromethyl)phenylboronic acid (CAS 2096341-51-2)
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