(2R)-1-tert-butoxycarbonyl-2-(4-tert-butylbenzyl)proline (2R)-1-tert-butoxycarbonyl-2-[(4-tert-butylphenyl)methyl]pyrrolidine-2-carboxylic acid (2R)-2-[(4-tert-butylphenyl)methyl]-1-[(2-methylpropan-2-yl)oxy-oxomethyl]-2-pyrrolidinecarboxylic acid (2R)-2-[(4-tert-butylphenyl)methyl]-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid 957310-66-6 Boc-(R)-alpha-(4-tert-butylphenyl)-proline CAS 957310-66-6

Purity 97%+In StockPharmaceutical Standards
CAS No.957310-66-6
Molecular FormulaC21H37NO4
Molecular Weight367.52 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2R)-1-tert-butoxycarbonyl-2-(4-tert-butylbenzyl)proline (2R)-1-tert-butoxycarbonyl-2-[(4-tert-butylphenyl)methyl]pyrrolidine-2-carboxylic acid (2R)-2-[(4-tert-butylphenyl)methyl]-1-[(2-methylpropan-2-yl)oxy-oxomethyl]-2-pyrrolidinecarboxylic acid (2R)-2-[(4-tert-butylphenyl)methyl]-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid 957310-66-6 Boc-(R)-alpha-(4-tert-butylphenyl)-proline CAS 957310-66-6 chemical structure

Description

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

(2R)-1-tert-butoxycarbonyl-2-(4-tert-butylbenzyl)proline (2R)-1-tert-butoxycarbonyl-2-[(4-tert-butylphenyl)methyl]pyrrolidine-2-carboxylic acid (2R)-2-[(4-tert-butylphenyl)methyl]-1-[(2-methylpropan-2-yl)oxy-oxomethyl]-2-pyrrolidinecarboxylic acid (2R)-2-[(4-tert-butylphenyl)methyl]-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid 957310-66-6 Boc-(R)-alpha-(4-tert-butylphenyl)-proline (CAS 957310-66-6) is a high-purity analytical reference standard with the molecular formula C21H37NO4 and a molecular weight of 367.52 g/mol.

The molecular framework of (2R)-1-tert-butoxycarbonyl-2-(4-tert-butylbenzyl)proline (2R)-1-tert-butoxycarbonyl-2-[(4-tert-butylphenyl)methyl]pyrrolidine-2-carboxylic acid (2R)-2-[(4-tert-butylphenyl)methyl]-1-[(2-methylpropan-2-yl)oxy-oxomethyl]-2-pyrrolidinecarboxylic acid (2R)-2-[(4-tert-butylphenyl)methyl]-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid 957310-66-6 Boc-(R)-alpha-(4-tert-butylphenyl)-proline (C21H37NO4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

As a certified reference material (CRM), (2R)-1-tert-butoxycarbonyl-2-(4-tert-butylbenzyl)proline (2R)-1-tert-butoxycarbonyl-2-[(4-tert-butylphenyl)methyl]pyrrolidine-2-carboxylic acid (2R)-2-[(4-tert-butylphenyl)methyl]-1-[(2-methylpropan-2-yl)oxy-oxomethyl]-2-pyrrolidinecarboxylic acid (2R)-2-[(4-tert-butylphenyl)methyl]-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid 957310-66-6 Boc-(R)-alpha-(4-tert-butylphenyl)-proline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC21H37NO4
Molecular Weight367.52 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Nitrogen Atoms1

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