1-(6-Chloropyridin-2-yl)piperazine hydrochloride CAS 95884-49-4
| CAS No. | 95884-49-4 |
| Molecular Formula | C9H12ClN3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-(6-Chloropyridin-2-yl)piperazine hydrochloride (CAS 95884-49-4) is a high-purity analytical reference standard with the molecular formula C9H12ClN3HCl and a molecular weight of 234.12 g/mol.
The molecular framework of 1-(6-Chloropyridin-2-yl)piperazine hydrochloride (C9H12ClN3HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 1-(6-Chloropyridin-2-yl)piperazine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H12ClN3 HCl |
| Molecular Weight | 234.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloropyridin Standards
- 3-(2-Chloropyridin-3-yl)propan-1-amine (CAS 1000512-13-9)
- 2-(4-chloropyridin-2-yl)acetonitrile (CAS 1000515-40-1)
- 2-(5-Chloropyridin-2-yl)acetic acid (CAS 1000522-43-9)
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- 2-(4-Chloropyridin-3-yl)acetic acid (CAS 1000567-15-6)
Recommended Standards
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- 4,4-Dimethylhex-2-ynoic acid (CAS 1343080-02-3)
- Amiodarone Impurity 18 (CAS 23349-86-2)
- 2-(4-Chloro-2-methoxyphenyl)ethan-1-ol (CAS 193290-24-3)
- 1-(2-phenylethyl)-1H-pyrrole-2-carboxylic acid (CAS 62541-29-1)
- (R)-2-((tert-butoxycarbonyl)(methyl)amino)hexanoic acid (CAS 161450-84-6)
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- 7-Bromo-6-methoxyquinoline (CAS 103028-33-7)
- Glucagon receptor antagonist I (CAS 438618-32-7)
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