4-Iodo-2,7-naphthyridin-1-amine CAS 959558-53-3
| CAS No. | 959558-53-3 |
| Molecular Formula | C8H6IN3 |
| Molecular Weight | 271.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Iodo-2,7-naphthyridin-1-amine.
4-Iodo-2,7-naphthyridin-1-amine (CAS 959558-53-3) is a high-purity analytical reference standard with the molecular formula C8H6IN3 and a molecular weight of 271.06 g/mol.
The molecular framework of 4-Iodo-2,7-naphthyridin-1-amine (C8H6IN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Iodo-2,7-naphthyridin-1-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6IN3 |
| Molecular Weight | 271.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Iodo Standards
- 4-Iodo-1,5-naphthyridin-3-amine (CAS 1261365-55-2)
- 3-(4-Iodo-1H-pyrazol-1-yl)pyridine (CAS 1306604-89-6)
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- 2-(4-Iodo-1H-pyrazol-1-yl)pyridine (CAS 777881-98-8)
- 2-(4-Iodo-1H-pyrazol-5-yl)pyridine (CAS 746668-75-7)
- 4-iodo-1,7-naphthyridin-3-amine (CAS 2820501-67-3)
- 4-iodo-1,8-naphthyridin-3-amine (CAS 2820501-62-8)
- 2-Iodo-5-phenyloxazole (CAS 1019654-82-0)
Recommended Standards
- 5-bromo-6-methoxybenzofuran-2-carboxylic acid (CAS 20073-19-2)
- 5-Iodoquinoxalin-6-amine (CAS 2174002-51-6)
- 4-(Bromomethyl)-5,7-dihydroxy-2H-chromen-2-one (CAS 90059-74-8)
- 6-bromo-4-hydroxy-7-methoxy-chromen-2-one (CAS 2883704-04-7)
- 6-Fluoro-7-methylquinolin-8-amine (CAS 1420791-63-4)
- 2-oxo-3-(propan-2-yl)-2,3-dihydro-1H-1,3-benzodiazole-5-carboxylic acid (CAS 1548186-68-0)
- 3-(pyridin-4-ylmethoxy)pyridin-2-amine (CAS 96428-83-0)
- (S)-4-(3-(but-2-ynamido)piperidin-1-yl)-5-fluoro-2,3-dimethyl-1H-indole-7-carboxamide (CAS 1912445-55-6)
- 2-(Bromomethyl)-7-ethoxybenzo[d]oxazole (CAS 1804104-54-8)
- 4-Butoxy-2,6-difluorobenzenesulfonyl chloride (CAS 1706431-01-7)
- 1-[2-[4-[6-Methoxy-2-(2,3,4,5,6-pentadeuteriophenyl)-3,4-dihydronaphthalen-1-yl]phenoxy]ethyl]pyrrolidine;hydrochloride (CAS 1794766-71-4)
- N,N-Diphenyl-4-(((4-vinylbenzyl)oxy)methyl)aniline (CAS 229323-80-2)
- N-(2-Oxo-1,2,3,4-tetrahydroquinolin-8-yl)acetamide (CAS 81840-12-2)
- [D-Ser6]-Semaglutide (CAS CATO-C4X-2226287)
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