Boc-(R)-α-(3-trifluoromethyl-benzyl)-proline CAS 959576-50-2
| CAS No. | 959576-50-2 |
| Molecular Formula | C18H22F3NO4 |
| Molecular Weight | 373.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Boc-(R)-α-(3-trifluoromethyl-benzyl)-proline is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 373.37 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Boc-(R)-α-(3-trifluoromethyl-benzyl)-proline (CAS 959576-50-2) is a high-purity analytical reference standard with the molecular formula C18H22F3NO4 and a molecular weight of 373.37 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Boc-(R)-α-(3-trifluoromethyl-benzyl)-proline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H22F3NO4 |
| Molecular Weight | 373.37 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Boc-(R)-gamma-(3-trifluoromethylbenzyl)-L-proline (CAS 959582-85-5)
- Boc-(R)-α-(4-trifluoromethylbenzyl)-Pro-OH (CAS 957310-45-1)
- Boc-(R)-4-[2-(trifluoromethyl)benzyl]-L-proline (CAS 957311-13-6)
- Ethyl 1-[4-(2-thienyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 955965-08-9)
- 4-bromothieno[3,2-d]pyrimidine (CAS 16285-70-4)
- Methyl 5-amino-2-fluoro-4-(trifluoromethyl)benzoate (CAS 1806853-93-9)
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