N-Trityl Losartan Carboxylic Acid CAS 960231-60-1
| CAS No. | 960231-60-1 |
| Molecular Formula | C42H37ClN6O3 |
| Molecular Weight | 709.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-Trityl Losartan Carboxylic Acid (CAS 960231-60-1), molecular formula C42H37ClN6O3 and molecular weight 709.23 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, N-Trityl Losartan Carboxylic Acid (C42H37ClN6O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 27.0, corresponding to approximately 27 ring(s) or double-bond equivalent(s). With a molecular weight of 709.23 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C42H37ClN6O3 |
| Molecular Weight | 709.23 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 27.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related N Standards
- Trityl-PEG10-azide (CAS 877239-08-2)
- N-Trityl Candesartan Methyl Ester Methoxy Analogue (CAS 1797136-91-4)
- TRityl-peg8-bromide (CAS 1818294-38-0)
- Trityl-Losartan-d (CAS 1309283-24-6)
- N-Trityl Candesartan Methoxy Analogue (CAS 1246820-94-9)
- N-Trityl Losartan Isomer (CAS 150098-04-7)
- Trityl-PEG8-azide (CAS 1818294-30-2)
- N-Trityl Candesartan Cilexetil Methoxy Analogue (CAS 1797867-82-3)
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