4-Bromo-5-methyl-2-(pyridin-4-yl)thiazole CAS 960493-33-8
| CAS No. | 960493-33-8 |
| Molecular Formula | C9H7BrN2S |
| Molecular Weight | 255.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Bromo-5-methyl-2-(pyridin-4-yl)thiazole (CAS 960493-33-8) is a high-purity analytical reference standard with the molecular formula C9H7BrN2S and a molecular weight of 255.13 g/mol.
The molecular framework of 4-Bromo-5-methyl-2-(pyridin-4-yl)thiazole (C9H7BrN2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 4-Bromo-5-methyl-2-(pyridin-4-yl)thiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7BrN2S |
| Molecular Weight | 255.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bromo Standards
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- 3-(5-bromo-4-methyl-1,3-thiazol-2-yl)pyridine (CAS 1204608-91-2)
- 3-Bromo-4-methylbenzo[b]thiophene-2-carbaldehyde (CAS 1402144-47-1)
- 1-(5-Bromo-1-benzothiophen-3-yl)ethan-1-one (CAS 1423-63-8)
- 2-Benzyl-5-bromo-1,3,4-thiadiazole (CAS 412923-43-4)
- 2-Bromo-5-methyl-4-(pyridin-2-yl)thiazole (CAS 886370-92-9)
- 2-Bromo-5-methyl-4-(pyridin-3-yl)thiazole (CAS 886370-98-5)
- 2-Bromo-5-methyl-4-(pyridin-4-yl)thiazole (CAS 886371-04-6)
Recommended Standards
- 4-Bromo-5-methyl-2-(pyridin-3-yl)thiazole (CAS 960493-35-0)
- 4-Bromo-8-fluoro-1,2,3,5,6,7-hexahydro-s-indacene (CAS 2143028-79-7)
- 4-Bromo-5-methyl-2-(pyridin-2-yl)thiazole (CAS 850245-46-4)
- 5-(3-Bromophenyl)thiazol-2-amine (CAS 959986-17-5)
- N-(1-phenylethyl)cyclobutanamine (CAS 1250333-92-6)
- Phthalic Acid 4,5-cis-Dihydrodiol (CAS 130073-64-2)
- 3-Phenyl-1H-isochromen-1-one (CAS 4809-08-9)
- 5-(4-Fluorophenyl)-N-phenyl-1,3,4-thiadiazol-2-amine (CAS 827580-58-5)
- 5-(2-Methanesulfonylpropan-2-yl)-2H-1,2,3,4-tetrazole (CAS 2126177-26-0)
- Isoficusin A (CAS 1914963-20-4)
- 6-(2,2-Dimethyl-1,3-dioxolan-4-yl)pyridin-3-amine (CAS 1419604-69-5)
- 3,5-Difluorothiophenol (CAS 845823-02-1)
- 3-Chloro-5-methylphenylboronic Acid (CAS 913836-14-3)
- Exenatide Acetate (CAS 141732-76-5)
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