2,6-Dichloro-[1,3]thiazolo[4,5-b]pyridine CAS 960535-43-7
| CAS No. | 960535-43-7 |
| Molecular Formula | C6H2Cl2N2S |
| Molecular Weight | 205.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,6-Dichloro-[1,3]thiazolo[4,5-b]pyridine (CAS 960535-43-7) is a high-purity analytical reference standard with the molecular formula C6H2Cl2N2S and a molecular weight of 205.06 g/mol.
2,6-Dichloro-[1,3]thiazolo[4,5-b]pyridine (C6H2Cl2N2S) contains a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H2Cl2N2S |
| Molecular Weight | 205.06 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 2,5-Dichlorothiazolo[5,4-b]pyridine (CAS 857970-66-2)
- 2,6-Dichlorothiazolo[5,4-c]pyridine (CAS 2132382-58-0)
- 2,5-Dichlorothiazolo[4,5-b]pyridine (CAS 2567498-97-7)
- 2,7-Dichlorothiazolo[5,4-c]pyridine (CAS 884860-61-1)
- Demecolcine (CAS 477-30-5)
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- 4-Methyl-N-(2-morpholinoquinazolin-4-yl)benzenesulfonamide (CAS 61335-55-5)
- Levocabastine Impurity 4 (CAS 25115-74-6)
- (4S)-2-[2-[Bis[3,5-bis(trifluoromethyl)phenyl]phosphino]phenyl]-4,5-dihydro-4-(1-methylethyl)oxazole (CAS 180260-73-5)
- Ethyl Lauroyl Arginate Hydrochloride (CAS 60372-77-2)
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