N-(4-chlorophenyl)-N-(o-tolyl)glycine CAS 96523-46-5
| CAS No. | 96523-46-5 |
| Molecular Formula | C15H14ClNO2 |
| Molecular Weight | 275.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(4-chlorophenyl)-N-(o-tolyl)glycine.
CATO supplies N-(4-chlorophenyl)-N-(o-tolyl)glycine (CAS 96523-46-5), a certified reference material (molecular formula C15H14ClNO2, MW 275.73 g/mol) for analytical method development and quality control.
The molecular framework of N-(4-chlorophenyl)-N-(o-tolyl)glycine (C15H14ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(4-chlorophenyl)-N-(o-tolyl)glycine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H14ClNO2 |
| Molecular Weight | 275.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- N-[(4-Chlorophenyl)-(2-hydroxyphenyl) methyl]acetamide (CAS 1010728-97-8)
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- n-(4-Chlorophenyl)-2-[(pyridin-3-ylmethyl)amino]acetamide (CAS 1040053-61-9)
- 2-((4-Chlorophenyl)(p-tolyl)amino)acetic acid (CAS 105885-81-2)
- Ethyl 6-(4-chlorophenyl)-2-methylnicotinate (CAS 108715-11-3)
- N-(4-Chlorophenyl)-N-(furan-2-ylmethyl)cyclopropanecarboxamide (CAS 114215-24-6)
- 2-(4-Chlorophenyl)-2-[(3-methylphenyl)amino]acetic acid (CAS 116340-30-8)
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Recommended Standards
- N-(4-Chlorobenzyl)-4-methoxybenzamide (CAS 351988-72-2)
- N-(5-chloro-2-hydroxyphenyl)-3-phenylpropanamide (CAS 86886-78-4)
- N-(4-Chlorobenzyl)-2-methoxybenzamide (CAS 331989-09-4)
- N-(5-Chloro-2-methylphenyl)-2-methoxybenzamide (CAS 331436-20-5)
- Methyl 2,4-Difluoro-5-nitrobenzoate (CAS 125568-71-0)
- 4-Fluoro-3-methylbenzotrifluoride (CAS 74483-52-6)
- 1-(2-(4-Chlorophenyl)acetyl)azetidine-3-carboxylic acid (CAS 1408485-12-0)
- 4-Bromo-3-chloro-N-methyl-N-phenylbenzamide (CAS 1529257-64-4)
- Benserazide impurity 49 (CAS CATO-C4X-142749)
- (R)-phenyl((S)-pyrrolidin-2-yl)methanol (CAS 74936-95-1)
- 1-(4-Chlorophenyl)-5-phenyl-1H-pyrazole (CAS 299162-82-6)
- 5-(3-Fluorophenyl)-3-methyl-1,2,4-oxadiazole (CAS 343771-07-3)
- 2-(4-Bromo-1-methyl-1H-pyrazol-3-yl)ethan-1-ol (CAS 1780333-86-9)
- Tirzepatide Impurity 50 (CAS CATO-C4X-324050)
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