Pregabalin Impurity 78 CAS 96914-67-9
| CAS No. | 96914-67-9 |
| Molecular Formula | C9H13NO2 |
| Molecular Weight | 167.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Pregabalin Impurity 78 (CAS 96914-67-9) is a certified pharmaceutical impurity reference standard with the molecular formula C9H13NO2 and a molecular weight of 167.21 g/mol.
The molecular framework of Pregabalin Impurity 78 (C9H13NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Pregabalin Impurity 78 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H13NO2 |
| Molecular Weight | 167.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 1 |
Related Pregabalin Standards
- Pregabalin Impurity 132 (CAS CATO-C4X-1312132)
- Pregabalin Impurity 133 (CAS CATO-C4X-1312133)
- Pregabalin Impurity 3 (CAS 916982-10-0)
- Pregabalin Impurity 139 (CAS CATO-C4X-1312139)
- pregabalin Impurity 71 (CAS 185815-59-2)
- Pregabalin-d4 (CAS 1276197-54-6)
- Pregabalin Impurity 135 (CAS CATO-C4X-1312135)
- Pregabalin Impurity 147 (CAS CATO-C4X-1312147)
Recommended Standards
- Buspirone EP Impurity K (CAS 1075-89-4)
- Sunitinib Impurity 3 (CAS 2199-51-1)
- Tirofiban Impurity 30 (CAS CATO-C4X-125430)
- Naphazoline EP Impurity C (CAS 132-75-2)
- Luliconazole impurity 25 (CAS CATO-C4X-285325)
- Timolol EP Impurity B（S-Isomer) (CAS 158636-96-5)
- Teprenone Impurity 24 (CAS CATO-C4X-208124)
- 5-Benzyl-6-chloro-N,N-diethyl-2-methylpyrimidin-4-amine (CAS 500156-07-0)
- Clomifene EP Impurity A (CAS 19957-52-9)
- N-(4-Methoxyphenyl)-1,2,3,4-tetrahydroacridine-9-carboxamide (CAS 74376-58-2)
- Ethyl 7-isopropyl-1H-indole-2-carboxylate (CAS 881041-05-0)
- Dihexadecyl disulfide (CAS 1561-75-7)
- 3-(4-Isopropoxy-3-methoxyphenyl)-1H-pyrazole-5-carboxylic acid (CAS 1273554-08-7)
- Semaglutide Impurity 143 (CAS CATO-C4X-2226143)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com