1-Benzyl-4-Cyano-4-(Para-Toluidino)-Piperidine CAS 972-19-0
| CAS No. | 972-19-0 |
| Molecular Formula | C20H23N3 |
| Molecular Weight | 305.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-Benzyl-4-Cyano-4-(Para-Toluidino)-Piperidine (C20H23N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
1-Benzyl-4-Cyano-4-(Para-Toluidino)-Piperidine (CAS 972-19-0), molecular formula C20H23N3 and molecular weight 305.42 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Benzyl-4-Cyano-4-(Para-Toluidino)-Piperidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H23N3 |
| Molecular Weight | 305.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 3 |
Related Benzyl Standards
- 1-Benzyl-4-cyano-4-(m-toluidino)-piperidine (CAS 972-18-9)
- 4-Cyano-5-(cyclopropanecarboxamido)-N,N-diethyl-3-methylthiophene-2-carboxamide (CAS 438613-93-5)
- N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-2-morpholinoacetamide (CAS 58125-32-9)
- 4-Cyano-3-(4-methoxyphenyl)-5-(methylthio)thiophene-2-carboxylic acid (CAS 116493-07-3)
- 4-Cyano-N-(4-phenylthiazol-2-yl)benzamide (CAS 313662-30-5)
- (E)-2-Cyano-2-(5-ethyl-3-(4-fluorophenyl)-4-oxothiazolidin-2-ylidene)acetamide (CAS 1164503-76-7)
- Benzyl 6-cyano-3,4-dihydro-2,4-methano-1,5-naphthyridine-1(2H)-carboxylate (CAS 2417970-26-2)
- Methyl 1-(cyano(1-methyl-1H-pyrrol-2-yl)methyl)isoquinoline-4-carboxylate (CAS 439108-16-4)
Recommended Standards
- 2-((5-Methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)(octyl)amino)ethanol (CAS 61993-92-8)
- (S)-tert-Butyl 3-methyl-4-(2-(pyridin-3-yl)ethyl)piperazine-1-carboxylate (CAS 2602340-68-9)
- 2-(1-(2-Methylbenzyl)piperidin-4-yl)-1H-benzo[d]imidazole (CAS 887215-61-4)
- (S)-2-(1,4-Dibenzylpiperazin-2-yl)acetonitrile (CAS 2225787-92-6)
- 1-(1,2,4-oxadiazol-3-ylmethyl)piperazine dihydrochloride (CAS 1258639-75-6)
- (S)-cyclopentyl(2-methylpiperazin-1-yl)methanone (CAS 1568094-30-3)
- 1-{[(tert-butoxy)carbonyl]amino}-3,3-difluorocyclopentane-1-carboxylic acid (CAS 1936649-94-3)
- 2-(2-(Thiophen-3-yl)phenyl)acetic acid (CAS 2004388-06-9)
- 2-(2,6-Dichlorophenyl)-3-oxobutanenitrile (CAS 186196-04-3)
- (5-Chloro-2-iodophenyl)methanamine (CAS 439117-11-0)
- tert-Butyl ((1R,2R)-2-(fluoromethyl)cyclobutyl)carbamate (CAS 2581763-00-8)
- Ethyl quinoxaline-2-carboxylate (CAS 7065-23-8)
- 2-Chloro-4-nitrobenzamidine (CAS 1260876-52-5)
- Glucagon receptor antagonists-2 (CAS 202917-18-8)
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