8-Amino-6-Fluoro-9-Ribofuranosyl-9H-Purine CAS 97229-54-4
| CAS No. | 97229-54-4 |
| Molecular Formula | C10H12FN5O4 |
| Molecular Weight | 285.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 8-Amino-6-Fluoro-9-Ribofuranosyl-9H-Purine (C10H12FN5O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 8-Amino-6-Fluoro-9-Ribofuranosyl-9H-Purine (CAS 97229-54-4), a certified reference material (molecular formula C10H12FN5O4, MW 285.23 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 8-Amino-6-Fluoro-9-Ribofuranosyl-9H-Purine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12FN5O4 |
| Molecular Weight | 285.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Amino Standards
- 2-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one (CAS 103884-98-6)
- 4-{[4-amino-3-(trifluoromethyl)-1h-pyrazol-1-yl]methyl}benzoic acid (CAS 1006433-86-8)
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Recommended Standards
- 7-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoro-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one (CAS 952429-17-3)
- Clofarabine Impurity 16 (CAS 899827-82-8)
- 5-(4-Fluorophenyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole (CAS 421581-70-6)
- N-((2,6-difluorobenzoyl)oxy)-1,2,3-thiadiazole-4-carboxamide (CAS 860609-70-7)
- 2-Bromo-N-(tetrahydro-2H-pyran-4-yl)propanamide (CAS 1334495-39-4)
- 8-((2-Chloro-3-((10,11-dihydro-9H-benzo[a]xanthen-8-yl)methylene)cyclohex-1-enyl)methylene)-8,9,10,11-tetrahydrobenzo[a]xanthenium perchlorate (CAS 62580-63-6)
- 6-Fluoro-4-oxo-7-(pyrrolidin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 1707375-54-9)
- N-(7-Chloro-4-methoxybenzo[d]thiazol-2-yl)-1-ethyl-1H-pyrazole-3-carboxamide (CAS 1171505-98-8)
- 2-(Cyclopropylmethoxy)-3-fluoroaniline (CAS 1369809-67-5)
- 2,6-Dichloro-3-hydroxypyridine (CAS 52764-11-1)
- 2-(3-Chloro-4-methoxybenzylidene)malononitrile (CAS 362721-80-0)
- 1-(4-tert-Butylphenyl)-3-(3-(isopropylamino)propyl)urea (CAS 1395492-64-4)
- tert-Butyl 11-oxo-5,10-diazaspiro[5.5]undecane-5-carboxylate (CAS 1221818-91-2)
- (10-31)Semaglutide (CAS CATO-C4X-2226283)
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