Ethyl 3-(2,6-Difluorophenyl)-3-oxopropionate CAS 97305-12-9
| CAS No. | 97305-12-9 |
| Molecular Formula | C11H10F2O3 |
| Molecular Weight | 228.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Ethyl 3-(2,6-Difluorophenyl)-3-oxopropionate (CAS 97305-12-9), molecular formula C11H10F2O3 and molecular weight 228.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 3-(2,6-Difluorophenyl)-3-oxopropionate (C11H10F2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10F2O3 |
| Molecular Weight | 228.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
Related Ethyl Standards
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- 1-(2,3-Difluorophenyl)-2-(1,3-dioxolan-2-yl)ethan-1-one (CAS 1263365-74-7)
- 1-(2,4-Difluorophenyl)-2-(1,3-dioxolan-2-yl)ethan-1-one (CAS 1263365-97-4)
- 1-(3,4-Difluorophenyl)-2-(1,3-dioxolan-2-yl)ethan-1-one (CAS 1263365-98-5)
- 1-(2,6-Difluorophenyl)-2-(1,3-dioxolan-2-yl)ethan-1-one (CAS 1263366-03-5)
Recommended Standards
- Ethyl 3-(2,5-Difluorophenyl)-3-oxopropionate (CAS 887267-53-0)
- Ethyl 3-(3,4-Difluorophenyl)-3-oxopropanoate (CAS 252955-07-0)
- Ethyl 3-(2,4-Difluorophenyl)-3-oxopropionate (CAS 58101-23-8)
- Ethyl 3-(3,5-Difluorophenyl)-3-oxopropionate (CAS 359424-42-3)
- 7-Bromo-2-cyclopentylphthalazin-1(2H)-one (CAS 1437436-25-3)
- 1-(2,5-Dichlorophenyl)thiourea (CAS 4949-85-3)
- 5-(Cyclopropylmethyl)-2-methylphenol (CAS 1243353-88-9)
- 1-Chloro-3-(pent-4-en-1-yl)benzene (CAS 114423-29-9)
- Rotigotine impurity 22 (CAS CATO-C4X-192722)
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- N-(2,2,2-trifluoroethyl)-5,6,7,8-tetrahydroquinolin-8-amine (CAS 1432679-46-3)
- 4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride (CAS 1209254-98-7)
- 6-methoxy-3-nitro-2H-chromene (CAS 92210-61-2)
- Tirzepatide Impurity 45 (CAS CATO-C4X-324045)
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