1-(2-Chloro-1,1,2-trifluoroethoxy)-4-methoxybenzene CAS 97675-21-3
| CAS No. | 97675-21-3 |
| Molecular Formula | C9H8ClF3O2 |
| Molecular Weight | 240.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2-Chloro-1,1,2-trifluoroethoxy)-4-methoxybenzene (C9H8ClF3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 1-(2-Chloro-1,1,2-trifluoroethoxy)-4-methoxybenzene (CAS 97675-21-3), a certified reference material (molecular formula C9H8ClF3O2, MW 240.61 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(2-Chloro-1,1,2-trifluoroethoxy)-4-methoxybenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8ClF3O2 |
| Molecular Weight | 240.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-[[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]amino]ethanol (CAS 1053656-91-9)
- 2-(6-Chloro-4-(trifluoromethyl)-pyridin-2-ylamino)ethanol (CAS 1089330-40-4)
- 5-(4-Chloro-2-fluorophenyl)furan-2-carboxylic acid (CAS 1094322-52-7)
- 1-(3-Chloro-4-methoxyphenyl)-2,2,2-trifluoroethan-1-ol (CAS 1250312-03-8)
- 4-(2-Chloro-1,1,2-trifluoroethoxy)-2-methylphenol (CAS 129670-05-9)
- 1-Chloro-3-(methoxymethoxy)-5-(trifluoromethyl)benzene (CAS 1415130-83-4)
- 1-(4-Chloro-3-methoxyphenyl)-2,2,2-trifluoroethan-1-ol (CAS 1520692-60-7)
- 6-Chloro-N4-Ethyl-2-(Trifluoromethyl)-4,5-Pyrimidinediamine (CAS 1810-35-1)
Recommended Standards
- 2-Chloro-1-(methoxymethoxy)-4-(trifluoromethyl)benzene (CAS 1881330-46-6)
- 1-(5-Chloro-2-methoxyphenyl)-2,2,2-trifluoroethan-1-ol (CAS 923170-54-1)
- 1-Chloro-3-ethoxy-5-(trifluoromethoxy)benzene (CAS 1881290-23-8)
- 5-(3-Chloro-4-fluorophenyl)furan-2-carboxylic acid (CAS 496044-15-6)
- 5-Chloro-3-hydrazinylpyridazin-4-amine (CAS 53180-75-9)
- 4-Chloro-5-fluoroindole-3-acetic acid (CAS 1227573-30-9)
- Methyl 2-(benzo[d][1,3]dioxol-5-yl)-2-oxoacetate (CAS 157530-74-0)
- Ethyl 3,5-Dimethylpyrazole-4-carboxylate (CAS 35691-93-1)
- 1-(3,4-Dichlorobenzyl)-4-isothiocyanato-3,5-dimethyl-1h-pyrazole (CAS 1006482-53-6)
- Sodium Butyrate-3,3,4,4,4-d5 (CAS 204244-79-1)
- (R,S)-Nornicotine-d4 (pyridine-d4) (CAS 66148-18-3)
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- Clindamycin Impurity 58 (CAS CATO-C4X-134158)
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