4-Ethoxy-3-fluorophenol CAS 98121-48-3
| CAS No. | 98121-48-3 |
| Molecular Formula | C8H9FO2 |
| Molecular Weight | 156.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Ethoxy-3-fluorophenol.
CATO supplies 4-Ethoxy-3-fluorophenol (CAS 98121-48-3), a certified reference material (molecular formula C8H9FO2, MW 156.15 g/mol) for analytical method development and quality control.
4-Ethoxy-3-fluorophenol (C8H9FO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Ethoxy-3-fluorophenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9FO2 |
| Molecular Weight | 156.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
Related Ethoxy Standards
- 3-Ethoxy-2-fluorophenol (CAS 1191998-59-0)
- 4-Ethoxy-2-fluorophenol (CAS 1196486-63-1)
- 3-Ethoxy-4-fluorophenol (CAS 1443055-75-1)
- 3-Ethoxy-5-fluorophenol (CAS 1443055-88-6)
- 2-Ethoxy-3-fluorophenol (CAS 909302-85-8)
- 2-Ethoxy-5-fluorophenol (CAS 376600-64-5)
- 2-Ethoxy-6-fluorophenol (CAS 868761-39-1)
- 5-Ethoxy-2-fluorophenol (CAS 577793-66-9)
Recommended Standards
- 4-Amino-3-hydrazono-6-methyl-3,4-dihydro-1,2,4-triazin-5(2h)-one (CAS 89124-32-3)
- 4-Fluoro-1,2-dimethoxybenzene (CAS 398-62-9)
- 3-Fluoro-4-methoxybenzyl alcohol (CAS 96047-32-4)
- 4-Fluoro-2-(methoxymethyl)phenol (CAS 2222511-96-6)
- 17a(H),21a(H)-(22RS)-Bishomohopane (CAS 105498-25-7)
- 3-(3-Chlorophenyl)-1-cyclohexyl-1-isopropylurea (CAS 197171-00-9)
- (5-(Trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)methanol (CAS 1779974-61-6)
- Methyl Diethyldithiocarbamate-d3 (CAS 1246816-30-7)
- 5-[1-(4-Chlorobenzenesulfonyl)pyrrolidin-2-yl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole (CAS 478045-81-7)
- Zidovudine-d4 (CAS CATO-C4X-178320)
- (E)-[(2-{[(4-chlorophenyl)methyl]sulfanyl}quinolin-3-yl)methylidene][(4-methoxyphenyl)methoxy]amine (CAS 478065-90-6)
- 1-Benzyl-2-(6-chloropyridin-3-yl)-5,6-dimethyl-1H-1,3-benzodiazole (CAS 337920-59-9)
- Methyl 4-amino-5-fluoronicotinate (CAS 1806682-19-8)
- Peptide Fmoc-Thi-Thi-OH (CAS CATO-CPTD788552)
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