4-Chloro-6-methylpyrimidine-2-carboxamide CAS 98142-20-2
| CAS No. | 98142-20-2 |
| Molecular Formula | C6H6ClN3O |
| Molecular Weight | 171.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-Chloro-6-methylpyrimidine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 4-Chloro-6-methylpyrimidine-2-carboxamide (CAS 98142-20-2), a certified reference material (molecular formula C6H6ClN3O, MW 171.58 g/mol) for analytical method development and quality control.
The molecular framework of 4-Chloro-6-methylpyrimidine-2-carboxamide (C6H6ClN3O) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H6ClN3O |
| Molecular Weight | 171.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 3-chloro-4-hydroxybenzamide (CAS 1007578-86-0)
- 4-Chloro-2-methoxynicotinaldehyde (CAS 1008451-58-8)
- 6-Chloro-N'-hydroxypicolinimidamide (CAS 1042151-12-1)
- 2-Chloro-4-hydroxybenzamide (CAS 1046818-83-0)
- 2-Chloro-6-hydroxybenzamide (CAS 1056958-24-7)
- 4-Chloro-5-methoxypyridine-2-carbaldehyde (CAS 1060801-63-9)
- 2-Chloro-5-methoxyisonicotinaldehyde (CAS 1060801-65-1)
- 6-Chloro-5-methoxynicotinaldehyde (CAS 1060801-67-3)
Recommended Standards
- 4-Chloro-6-methylpyridine-2-carboxylic Acid (CAS 30235-19-9)
- 5-(Chloromethyl)picolinic acid (CAS 53234-53-0)
- 4-Chloro-6,7-dihydro-5H-pyrimido[4,5-b][1,4]oxazine (CAS 2069182-22-3)
- 5-Chloro-3-methylpyridine-2-carboxylic acid (CAS 886365-46-4)
- 2-(2-Amino-4-methanesulfonylphenoxy)ethan-1-ol (CAS 1153121-95-9)
- 2-Cyclopropoxy-N,N-dimethyl-4-(methylsulfonamido)benzamide (CAS 1243359-30-9)
- 4-{3-[(Methylanilino)carbonyl]anilino}-4-oxobutanoic acid (CAS 941466-07-5)
- 2,2-Difluorocyclohexanamine Hydrochloride (CAS 921602-83-7)
- Biotin-PEG8-amine (CAS 2183447-27-8)
- 1-(2,4-Dihydroxy-3-(trifluoromethyl)phenyl)-2-methylpropan-1-one (CAS 1204737-93-8)
- Methyl 6-Methylquinoline-3-carboxylate (CAS 1238846-51-9)
- 2,5-Dioxopyrrolidin-1-yl 2-(p-tolyloxy)acetate (CAS 1150314-11-6)
- 2-(Butylsulfonyl)-6-(cyclohexylmethoxy)pyrimidin-4-amine (CAS 651733-96-9)
- Tumor Targeted Pro-Apoptotic Peptide (CAS 1926163-30-5)
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