4-oxopyrrolidine-2-carboxylic acid hydrochloride CAS 98142-78-0
| CAS No. | 98142-78-0 |
| Molecular Formula | C5H7NO3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-oxopyrrolidine-2-carboxylic acid hydrochloride (CAS 98142-78-0), molecular formula C5H7NO3HCl and molecular weight 165.57 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-oxopyrrolidine-2-carboxylic acid hydrochloride (C5H7NO3HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 4-oxopyrrolidine-2-carboxylic acid hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H7NO3 HCl |
| Molecular Weight | 165.57 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related oxopyrrolidine Standards
- 1-Ethyl-5-oxopyrrolidine-2-carboxylic acid (CAS 1001390-60-8)
- 4-Methyl-5-oxopyrrolidine-3-carboxamide (CAS 107610-63-9)
- 1-Ethyl-5-oxopyrrolidine-3-carbohydrazide (CAS 1097826-77-1)
- 1-Benzyl-2-oxopyrrolidine-3-carboxylic acid (CAS 109859-99-6)
- (S)-5-oxopyrrolidine-3-carbaldehyde (CAS 1101167-75-2)
- 2-(2-(5-Oxopyrrolidine-2-carboxamido)thiazol-4-yl)acetic acid (CAS 1103834-16-7)
- Methyl 5-Oxopyrrolidine-3-acetate (CAS 1134289-71-6)
- 1-Benzyl-5-oxopyrrolidine-3-carbonyl chloride (CAS 114368-05-7)
Recommended Standards
- 2,3-Dihydro-1H-indol-1-yl(4-piperidinyl)methanonehydrochloride (CAS 1220021-30-6)
- 4-Amino-3-chloro-1-methylpyrazole (CAS 150187-11-4)
- (S)-1-[4-(Trifluoromethyl)phenyl]ethanol (CAS 99493-93-3)
- 2-(1-methylpiperidin-4-yl)ethan-1-ol (CAS 21156-84-3)
- 1-(2-Amino-6-chlorophenyl)-3-pyrrolidinol (CAS 1220037-83-1)
- 2-(1,1-Dioxo-tetrahydro-1lambda*6*-thiophen-3-ylamino)-pentanoic acid (CAS 1396967-41-1)
- (2-Bromo-4-fluoro-3-methoxyphenyl)methanol (CAS 2091677-32-4)
- 4-Methoxypyridin-2(1H)-one (CAS 52545-13-8)
- (1-Methyl-3-phenyl-propyl)-(tetrahydro-furan-2-ylmethyl)-amine hydrochloride (CAS 1185296-89-2)
- D-[Asp]9-Semaglutide (CAS CATO-CPTD788631)
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