1-Methyl-5-nitro-1H-pyrazolo[3,4-b]pyridine CAS 98157-49-4
| CAS No. | 98157-49-4 |
| Molecular Formula | C7H6N4O2 |
| Molecular Weight | 178.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-Methyl-5-nitro-1H-pyrazolo[3,4-b]pyridine (CAS 98157-49-4), a certified reference material (molecular formula C7H6N4O2, MW 178.15 g/mol) for analytical method development and quality control.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, 1-Methyl-5-nitro-1H-pyrazolo[3,4-b]pyridine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 178.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Methyl-5-nitro-1H-pyrazolo[3,4-b]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6N4O2 |
| Molecular Weight | 178.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 4 |
Related Methyl Standards
- 4-Nitro-1H-pyrrolo[2,3-b]pyridin-3-amine (CAS 1000340-42-0)
- 6-Nitro-1H-benzo[d]imidazol-4-amine (CAS 102169-82-4)
- 6-Nitro-1H-indazol-7-amine (CAS 102170-03-6)
- 4-Nitro-1H-indazol-5-amine (CAS 102170-46-7)
- 6-Nitro-1H-indazol-3-amine (CAS 1027259-01-3)
- 6-Nitro-1H-indazol-4-amine (CAS 1082041-92-6)
- 7-Methyl-8-nitro-[1,2,4]triazolo[1,5-a]pyridine (CAS 1150617-74-5)
- 3-Nitro-1H-pyrrolo[3,2-b]pyridin-6-amine (CAS 1190312-12-9)
Recommended Standards
- 1-Methyl-5-nitro-1H-benzo[d][1,2,3]triazole (CAS 25877-34-3)
- 2-(9H-Purin-9-yl)acetic acid (CAS 98550-24-4)
- 1-Methyl-1H-pyrazolo[3,4-c]pyridazine-4-carboxylic acid (CAS 2468993-21-5)
- 2-(methylamino)-5-nitropyridine-3-carbonitrile (CAS 31309-10-1)
- 1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-1,2,3-triazole (CAS 150366-82-8)
- (2E)-1-(4-Ethoxyphenyl)-3-(5-methylfuran-2-yl)prop-2-en-1-one (CAS 1354941-61-9)
- 2-Methyl-1-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazole-5-carboxylic acid (CAS 452088-74-3)
- 3-Chloro-1-methyl-1H-pyrazole-4-sulfonamide (CAS 101457-06-1)
- 4-((4-Chlorophenyl)((1-(1-phenylcyclobutyl)ethylidene)hydrazono)methyl)phenyl methanesulfonate (CAS 78929-83-6)
- (S)-3-amino-8-methoxy-1-methyl-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]azepin-2-one (CAS 2306252-55-9)
- 4-(Difluoromethoxy)-3-nitrobenzothioamide (CAS 1403567-57-6)
- Heptyl (S)-4-(1-amino-2,2,2-trifluoroethyl)benzoate (CAS 1213479-65-2)
- 1-Benzylazetidine-3,3-dicarboxylic acid (CAS 106014-87-3)
- Retatrutide (CAS 2381089-83-2)
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