Brexpiprazole Impurity 33 CAS 98327-87-8
| CAS No. | 98327-87-8 |
| Molecular Formula | C44H32P2 |
| Molecular Weight | 622.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Brexpiprazole Impurity 33 is closely related to organophosphorus functionality, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Brexpiprazole Impurity 33 (CAS 98327-87-8, C44H32P2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to organophosphorus functionality, a polycyclic aromatic system, Brexpiprazole Impurity 33 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 622.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Brexpiprazole Impurity 33 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C44H32P2 |
| Molecular Weight | 622.67 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 29.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
Related Brexpiprazole Standards
- Brexpiprazole impurity 116 (CAS CATO-C4X-1131116)
- Brexpiprazole Impurity 144 (CAS CATO-C4X-1131144)
- Brexpiprazole Impurity 148 (CAS CATO-C4X-1131148)
- Brexpiprazole Impurity 150 (CAS CATO-C4X-1131150)
- Brexpiprazole Impurity 26 (CAS 2094559-58-5)
- Brexpiprazole Impurity 49 (CAS 2116542-21-1)
- Brexpiprazole Impurity 75 (CAS CATO-C4X-113175)
- Brexpiprazole Impurity 38 (CAS CATO-C4X-113138)
Recommended Standards
- BINAP (CAS 76189-55-4)
- Ruilugoli lmpurity 134 (CAS CATO-C4X-2429134)
- 1,15-Bis(diphenylphosphino)-7,8,9,10-tetrahydro-6H-dibenzo[b,d][1,6]dioxacycloundecine (CAS 905714-09-2)
- Cathepsin G substrate (CAS 70967-91-8)
- Telmisartan Impurity 51 (CAS 99-36-5)
- Aclidinium bromide Impurity 15 (CAS CATO-C4X-132515)
- Allisartan Isoproxil Impurity 27 (CAS 947331-07-9)
- 2-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoindolin-1-one (CAS 1614234-01-3)
- Methyl(2-methylnaphthalen-1-yl)sulfane (CAS 350600-29-2)
- Methyl 3-(2-{[(4-fluorophenyl)carbamoyl]carbonyl}-1H-pyrrol-1-yl)-1-benzothiophene-2-carboxylate (CAS 477872-80-3)
- Ethyl 3-((4-(pyridin-2-yl)piperazin-1-yl)sulfonyl)benzo[b]thiophene-2-carboxylate (CAS 932464-69-2)
- 3-(1-(Aminomethyl)cyclopentyl)pentan-3-ol (CAS 1542681-12-8)
- 5-Chloro-1-methyl-3-phenyl-N-(4-(trifluoromethyl)phenyl)-1H-pyrazole-4-carboxamide (CAS 318237-82-0)
- Liraglutide Impurity 14 TFA Salt (CAS CATO-C4X-199214)
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