N-(4-Hydroxyphenyl)thiophene-2-carboxamide CAS 98902-53-5
| CAS No. | 98902-53-5 |
| Molecular Formula | C11H9NO2S |
| Molecular Weight | 219.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-(4-Hydroxyphenyl)thiophene-2-carboxamide (C11H9NO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
N-(4-Hydroxyphenyl)thiophene-2-carboxamide (CAS 98902-53-5), molecular formula C11H9NO2S and molecular weight 219.26 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(4-Hydroxyphenyl)thiophene-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H9NO2S |
| Molecular Weight | 219.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related N Standards
- n-(3-Hydroxyphenyl)thiophene-3-carboxamide (CAS 1038266-33-9)
- n-(4-Hydroxyphenyl)thiophene-3-carboxamide (CAS 1042593-15-6)
- n-(3-Hydroxyphenyl)thiophene-2-carboxamide (CAS 307525-91-3)
- 1-[4-(4-hydroxyphenyl)piperidin-1-yl]ethan-1-one (CAS 149354-13-2)
- 3-(3-Hydroxyphenyl)-1-methylazepan-2-one (CAS 71592-44-4)
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- 6-((2-Hydroxyphenyl)amino)pyrimidine-2,4(1H,3H)-dione (CAS 105147-86-2)
- 2-(3-(2-Hydroxyphenyl)-1H-1,2,4-triazol-5-yl)acetic acid (CAS 1146911-23-0)
Recommended Standards
- N-(4-Methylpyrimidin-2-yl)thiophene-2-carboxamide (CAS 664345-99-7)
- Methyl 5-(thiophen-3-yl)nicotinate (CAS 893735-04-1)
- N-benzyl-1,2,5-thiadiazole-3-carboxamide (CAS 709000-51-1)
- Methyl 5-(thiophen-2-yl)pyridine-3-carboxylate (CAS 893735-01-8)
- 2-((7-Cyano-3,4-dihydro-2H-1,4-ethano-1,5-naphthyridin-6-yl)thio)-N-(3,4-dimethoxyphenethyl)acetamide (CAS 728001-60-3)
- 4-Chloro-6-(6-(trifluoromethyl)pyridin-3-yl)pyrimidine (CAS 1590398-07-4)
- SN-38 Glucuronide (CAS 121080-63-5)
- 3-Nitro-4-(phenylsulfanyl)benzenecarbaldehyde O-methyloxime (CAS 477852-23-6)
- 1-(2-(6-(tert-Butylthio)pyridin-3-yl)pyrrolidin-1-yl)ethanone (CAS 1352540-02-3)
- Methyl furan-2-carbonyl(phenyl)carbamimidothioate (CAS 83790-80-1)
- 4-(2,4,5-Trichlorophenoxy)piperidine hydrochloride (CAS 1219981-42-6)
- 2,2’-Dimethylbenzil (CAS 2048-07-9)
- Dapagliflozin Impurity 161 (CAS CATO-C4X-1138161)
- Insulin Degludec Impurity 11 (CAS CATO-C4X-215711)
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