6-Fluoro-N-methyl-3-nitroquinolin-4-amine CAS 99009-92-4
| CAS No. | 99009-92-4 |
| Molecular Formula | C10H8FN3O2 |
| Molecular Weight | 221.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Fluoro-N-methyl-3-nitroquinolin-4-amine (CAS 99009-92-4) is a high-purity analytical reference standard with the molecular formula C10H8FN3O2 and a molecular weight of 221.19 g/mol.
6-Fluoro-N-methyl-3-nitroquinolin-4-amine (C10H8FN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8FN3O2 |
| Molecular Weight | 221.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluoro Standards
- 8-Fluoro-4-hydroxyquinoline-3-carbohydrazide (CAS 1018127-67-7)
- 6-Fluoro-4-oxo-1,4-dihydroquinoline-3-carbohydrazide (CAS 1018135-33-5)
- 1-(4-Fluoro-2-nitrophenyl)-2-methyl-1H-imidazole (CAS 1018150-88-3)
- 1-(2-Fluoro-4-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1040025-87-3)
- 1-(5-Fluoro-2-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1042534-83-7)
- 1-(3-Fluoro-4-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1042604-73-8)
- 1-(4-Fluoro-2-methylphenyl)-1h-1,2,3-triazole-4-carboxylic acid (CAS 1042604-81-8)
- 5-Fluoro-6-(phenylamino)pyrimidine-2,4(1H,3H)-dione (CAS 105950-49-0)
Recommended Standards
- 6-Fluoro-4-oxo-1,4-dihydroquinoline-3-carbohydrazide (CAS 915978-56-2)
- Methyl 3-fluoro-4-(1H-1,2,4-triazol-1-yl)benzoate (CAS 866009-43-0)
- 5-Amino-1-(4-fluorophenyl)-1h-1,2,3-triazole-4-carboxamide (CAS 606135-57-3)
- 3-(Trifluoromethoxy)benzothioamide (CAS 1053656-09-9)
- Benzyl cyclopropyl((1-(2-hydroxyethyl)piperidin-4-yl)methyl)carbamate (CAS 1353961-78-0)
- 1-([1,1'-Biphenyl]-4-ylmethyl)-4,6-difluoro-5-iodo-2-(methylthio)-1h-benzo[d]imidazole (CAS 1219741-32-8)
- tert-butyl 3-amino-3-carbamoylazetidine-1-carboxylate (CAS 1254120-14-3)
- 2-Amino-6-(2-chlorophenyl)-3,4,5,6-tetrahydropyrimidin-4-one (CAS 892761-30-7)
- 3-(4-Cyanophenyl)pentanedioic acid (CAS 952415-62-2)
- 1-(3,4-Dimethylphenyl)-5-methyl-1h-pyrazole-4-carboxylic acid (CAS 1204296-92-3)
- 1-Bromo-2-(3-bromo-2,2-dimethylpropyl)benzene (CAS 1488005-73-7)
- Thiocolchicoside EP Impurity H (10-Demethoxy Colchicoside) (CAS CATO-C4X-27704)
- Ethyl 3-amino-2-methylimidazo[1,2-a]pyridine-8-carboxylate (CAS 133427-91-5)
- Semaglutide impurity 91 (CAS CATO-C4X-222691)
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