1-Iodo-3-(methoxymethyl)benzene CAS 99221-26-8
| CAS No. | 99221-26-8 |
| Molecular Formula | C8H9IO |
| Molecular Weight | 248.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-Iodo-3-(methoxymethyl)benzene (CAS 99221-26-8), molecular formula C8H9IO and molecular weight 248.06 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Iodo-3-(methoxymethyl)benzene (C8H9IO) is characterized by a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9IO |
| Molecular Weight | 248.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | I-containing |
Related Iodo Standards
- (2-Iodo-3-methylphenyl)methanol (CAS 100959-88-4)
- 2-Iodo-4,5-dimethylphenol (CAS 106362-66-7)
- 4-Iodo-2,5-dimethylphenol (CAS 114971-53-8)
- (5-Iodo-2-methylphenyl)hydrazine (CAS 1195491-13-4)
- 5-Iodo-2-methylbenzyl Alcohol (CAS 1260242-01-0)
- (2-Iodo-4-methylphenyl)methanol (CAS 126156-20-5)
- (4-Iodo-2-methylphenyl)methanol (CAS 1261747-54-9)
- (2-Iodo-6-methylphenyl)methanol (CAS 1261794-19-7)
Recommended Standards
- 1-Iodo-2-methoxy-3-methylbenzene (CAS 25922-05-8)
- 1-Iodo-3-methoxy-2-methylbenzene (CAS 21093-09-4)
- 1-Iodo-2-(methoxymethyl)benzene (CAS 90003-91-1)
- 1-Iodo-4-(methoxymethyl)benzene (CAS 91912-54-8)
- 3-Amino-6'-methyl-2H-[1,3'-bipyridin]-2-one (CAS 2271471-46-4)
- 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-3-(o-tolyl)urea (CAS 935660-79-0)
- (1R,2S)-1-amino-1-(thiophen-2-yl)propan-2-ol (CAS 1269836-03-4)
- CAY10512 (CAS 139141-12-1)
- [(1-ethyl-1h-pyrazol-3-yl)methyl](methyl)amine (CAS 1002651-65-1)
- 2-(tert-Butyl)-7,8-dihydro-5(6H)-quinazolinone (CAS 499206-35-8)
- 2-(Difluoromethyl)-5-nitropyridin-4-ol (CAS 1805314-41-3)
- 3-Nitro-1-nonyl-1h-pyrazole (CAS 1240569-48-5)
- Methyl 1-((2-chlorophenoxy)methyl)-1h-pyrazole-3-carboxylate (CAS 958133-25-0)
- Insulin Degludec Impurity 28 (CAS CATO-C4X-215728)
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