3-Amino-8-hydroxy-2-methylquinazolin-4(3H)-one CAS 99358-69-7
| CAS No. | 99358-69-7 |
| Molecular Formula | C9H9N3O2 |
| Molecular Weight | 191.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Amino-8-hydroxy-2-methylquinazolin-4(3H)-one is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Amino-8-hydroxy-2-methylquinazolin-4(3H)-one (CAS 99358-69-7) is a high-purity analytical reference standard with the molecular formula C9H9N3O2 and a molecular weight of 191.19 g/mol.
3-Amino-8-hydroxy-2-methylquinazolin-4(3H)-one (C9H9N3O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H9N3O2 |
| Molecular Weight | 191.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 3 |
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Recommended Standards
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- 3-Benzotriazol-1-yl-propionic Acid (CAS 654-15-9)
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- 2-(Chloromethyl)-1-methyl-4-(trifluoromethyl)benzene (CAS 225656-63-3)
- N-(5,6-Dihydrobenzo[h]quinazolin-2-yl)-3-nitrobenzenecarboxamide (CAS 306979-38-4)
- ((4-Methylcyclohexyl)methyl)hydrazine (CAS 1355449-01-2)
- (3-Methoxyphenyl)(5-(phenoxymethyl)-1H-1,2,4-triazol-3-yl)methanamine (CAS 1707585-84-9)
- CAS 2375194-37-7 (CAS 2375194-37-7)
- (E)-1,1,1-trifluoro-4-(pyridin-3-ylamino)but-3-en-2-one (CAS 428842-24-4)
- 2-(4-(Chloromethyl)-1H-pyrazol-1-yl)pyridine hydrochloride (CAS 1449117-51-4)
- (S,S)-BPPM (CAS 61478-28-2)
- C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 127869-51-6)
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