2-Methoxyquinoline-6-carboxylic acid CAS 99472-03-4
| CAS No. | 99472-03-4 |
| Molecular Formula | C11H9NO3 |
| Molecular Weight | 203.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Methoxyquinoline-6-carboxylic acid.
CATO supplies 2-Methoxyquinoline-6-carboxylic acid (CAS 99472-03-4), a certified reference material (molecular formula C11H9NO3, MW 203.19 g/mol) for analytical method development and quality control.
The molecular framework of 2-Methoxyquinoline-6-carboxylic acid (C11H9NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Methoxyquinoline-6-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H9NO3 |
| Molecular Weight | 203.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 1 |
Related Methoxyquinoline Standards
- 2-methoxyquinoline-4-carboxylic Acid (CAS 10222-62-5)
- 8-Methoxyquinoline-4-carboxylic Acid (CAS 1092288-64-6)
- 7-Methoxyquinoline-8-carboxylic acid (CAS 1159427-80-1)
- 3-methoxyquinoline-4-carboxylic acid (CAS 1241386-37-7)
- 2-Methoxyquinoline-5-carboxylic acid (CAS 1339053-78-9)
- 5-Methoxyquinoline-3-carboxylic Acid (CAS 1361091-98-6)
- 2-Methoxyquinoline-7-carboxylic acid (CAS 1374258-40-8)
- 5-Methoxyquinoline-4-carboxylic acid (CAS 1474033-93-6)
Recommended Standards
- 2-Methoxyquinoline-3-carboxylic acid (CAS 70659-29-9)
- 2-Methyl-1-oxo-1,2-dihydroisoquinoline-3-carboxylic Acid (CAS 89806-32-6)
- 2-Methoxy-6-nitronaphthalene (CAS 4900-67-8)
- 2-Methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxylic acid (CAS 54931-62-3)
- 1-fluoro-3-hydroxy-cyclobutanecarbonitrile (CAS 1215071-22-9)
- 2-Chloro-3-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1416367-16-2)
- 2-Methylpropylhydrazine Hydrochloride (CAS 237064-47-0)
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- 2-(4-(Aminomethyl)-6-(difluoromethyl)-5-hydroxypyridin-2-yl)acetonitrile (CAS 1806946-56-4)
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