1-(Phenylsulfonyl)-1H-indole-3-carbonyl chloride CAS 99532-51-1
| CAS No. | 99532-51-1 |
| Molecular Formula | C15H10ClNO3S |
| Molecular Weight | 319.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 1-(Phenylsulfonyl)-1H-indole-3-carbonyl chloride (C15H10ClNO3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 319.76 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 1-(Phenylsulfonyl)-1H-indole-3-carbonyl chloride (CAS 99532-51-1), a certified reference material (molecular formula C15H10ClNO3S, MW 319.76 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10ClNO3S |
| Molecular Weight | 319.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Phenylsulfonyl Standards
- 1-(Phenylsulfonyl)-1H-indole-2-carbonyl chloride (CAS 342405-28-1)
- 2-Phenyl-2-[(phenylsulfonyl)amino]butanoic acid (CAS 361464-18-8)
- 4-(Phenylsulfonyl)-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid (CAS 1858251-66-7)
- 39082-53-6 1,1-Bis(phenylsulfonyl)ethylene MFCD00043149 ETHYLENE, 1,1-BIS-(PHENYLSULFONYL)- (CAS 39082-53-6)
- 5-(4-(Phenylsulfonyl)phenyl)-1H-1,2,4-triazole-3(2H)-thione (CAS 141212-52-4)
- 2-(phenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (CAS 1009266-12-9)
- 2-(Phenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-7-carboxylic acid (CAS 1956369-45-1)
- 1-(Phenylsulfonyl)-3-(p-tolylthio)propan-2-ol (CAS 338409-60-2)
Recommended Standards
- 2-(5-chlorothiophen-2-yl)-6-methoxyquinoline-4-carboxylic acid (CAS 897565-19-4)
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- 2,4-Thiophenedicarboxylic acid, 5-[(2-chloroacetyl)amino]-3-methyl-, 4-ethyl 2-methyl ester (CAS 300676-14-6)
- (E)-3-oxo-2-phenylbutanal O-(2-chloro-6-fluorobenzyl) oxime (CAS 339116-26-6)
- 1-(6-(4-Ethylpiperazin-1-yl)-4-methylpyridin-3-yl)propan-1-amine (CAS 1355220-25-5)
- 2-Bromo-4-formyl-6-methoxyphenyl 1-naphthoate (CAS 443294-58-4)
- 2-(4-(Difluoromethyl)-6-nitro-3-(trifluoromethoxy)pyridin-2-yl)acetic acid (CAS 1806774-19-5)
- 6'-Bromo-1',4'-dihydro-2'H-spiro[piperidine-4,3'-[1,8]naphthyridin]-2'-one (CAS 1416440-35-1)
- 2,4,6-Trichlorobenzene-1,3,5-tricarbaldehyde (CAS 14222-98-1)
- 6-(Benzyloxy)-4-chloro-5-methylpyrrolo[2,1-f][1,2,4]triazine (CAS 649736-27-6)
- [5-(Thiophen-2-yl)-1,2-oxazol-3-yl]methanol (CAS 194491-44-6)
- 3-(5-Bromo-2-chlorophenyl)-4-methyl-1h-pyrazol-5-amine (CAS 1187636-03-8)
- (E)-N'-[(2,6-Dichlorophenyl)methoxy]-N-{thieno[2,3-d]pyrimidin-4-yl}methanimidamide (CAS 477846-38-1)
- CGMP Dependent Kinase Inhibitor Peptide (CAS 82801-73-8)
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