4-Bromo-2-chlorobenzene-1-thiol CAS 99839-25-5
| CAS No. | 99839-25-5 |
| Molecular Formula | C6H4BrClS |
| Molecular Weight | 223.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Bromo-2-chlorobenzene-1-thiol (C6H4BrClS) is characterized by sulfur-containing functionality, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4-Bromo-2-chlorobenzene-1-thiol (CAS 99839-25-5) is a high-purity analytical reference standard with the molecular formula C6H4BrClS and a molecular weight of 223.52 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Bromo-2-chlorobenzene-1-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4BrClS |
| Molecular Weight | 223.52 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl/Br-containing |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 3-Bromo-5-chlorobenzenethiol (CAS 1263376-19-7)
- 2-Bromo-6-chlorobenzene-1-thiol (CAS 1263376-31-3)
- 3-Bromo-4-chlorobenzene-1-thiol (CAS 1263376-96-0)
- 2-Bromo-4-chlorobenzenethiol (CAS 54404-01-2)
- 2-Bromo-5-chlorobenzenethiol (CAS 54404-02-3)
- 4-Bromo-3-chlorobenzene-1-thiol (CAS 853308-08-4)
- 5-Bromo-2-chlorobenzenethiol (CAS 740806-63-7)
- 4-Bromo-1-(2-chloroethyl)-3-methyl-1H-pyrazole (CAS 108354-38-7)
Recommended Standards
- 1,2,4-Trichloro-3,5,6-trimethylbenzene (CAS 10203-45-9)
- 1,3-Dichloro-2-(3-chloropropyl)benzene (CAS 1057673-07-0)
- 1,2-Dichloro-3-(3-chloropropyl)benzene (CAS 859189-04-1)
- (2,2-Dichlorocyclopropyl)methanesulfonyl chloride (CAS 1146290-10-9)
- 4-(Azetidine-1-sulfonyl)-1h-pyrrole-2-carboxylic acid (CAS 1157026-93-1)
- 1-(4-Fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid (CAS 1220165-92-3)
- 4-Chloro-6-Nitro-Picolinic Acid (CAS 1393569-52-2)
- Ethyl 3,5-diethylbenzoate (CAS 1256482-41-3)
- 6-Chloro-8-nitro-4-oxo-4H-chromene-3-carbaldehyde (CAS 879559-53-2)
- Ruxolitinib Impurity 22 (CAS CATO-C4X-205822)
- 2-(butan-2-yl)piperidine hydrochloride (CAS 1334146-89-2)
- 1-(2-methoxyethyl)imidazolidine-2,4,5-trione (CAS 40411-22-1)
- 4-Bromo-2-(difluoromethyl)-3-methylpyridine-5-carbonyl chloride (CAS 1806995-46-9)
- Peptide Impurity 05 (CAS 2322924-83-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com