Labetalol EP Impurity D CAS CATO-C1829030
| CAS No. | CATO-C1829030 |
| Molecular Formula | C9H12N2O3 |
| Molecular Weight | 196.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Labetalol EP Impurity D (CAS CATO-C1829030), a pharmacopoeial impurity reference standard (molecular formula C9H12N2O3, MW 196.20 g/mol) used for the identification and quantification of trace impurities in APIs.
Labetalol EP Impurity D (C9H12N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H12N2O3 |
| Molecular Weight | 196.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Labetalol Standards
- Labetalol Impurity 66 (CAS CATO-C4X-246666)
- Labetalol Impurity 78 (CAS CATO-C4X-246678)
- Labetalol Impurity 60 (CAS CATO-C4X-246660)
- Labetalol Impurity 23 (CAS 2724509-52-6)
- Labetalol Impurity 22 (CAS 40187-51-7)
- Labetalol Impurity 21 (CAS 33254-88-5)
- Labetalol Impurity 29 (CAS 119021-71-5)
- Labetalol Impurity 55 (CAS CATO-C4X-246655)
Recommended Standards
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- Gliclazide EP Impurity G (CAS CATO-C4X-14497)
- Ramelteon Impurity N40 (CAS 1221160-70-8)
- Sotagliflozin Impurity 2 (CAS 1327165-94-5)
- 4-Nitrophenyl 4-6-O-benzylidene-β-D-glucopyranoside (CAS 83167-73-1)
- 2-(Butoxymethyl)benzaldehyde (CAS 1379066-26-8)
- 3-Amino-5-methyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one (CAS 205989-36-2)
- 3-Amino-n-(3-pyridinylmethyl)benzamide (CAS 25844-49-9)
- N-(3,5-Dichlorophenyl)-2-((3-ethyl-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 577763-67-8)
- 3-(Benzylsulfonyl)propanoic acid (CAS 90396-02-4)
- Semaglutide Impurity 180 (CAS CATO-C4X-2226180)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com