α-Ketoglutaric acid Dimer Impurity CAS CATO-C3D-5782
| CAS No. | CATO-C3D-5782 |
| Molecular Formula | C10H10O9 |
| Molecular Weight | 274.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies α-Ketoglutaric acid Dimer Impurity (CAS CATO-C3D-5782), a pharmacopoeial impurity reference standard (molecular formula C10H10O9, MW 274.18 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, α-Ketoglutaric acid Dimer Impurity (C10H10O9) contains a carbohydrate-derived structure. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 274.18 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), α-Ketoglutaric acid Dimer Impurity meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10O9 |
| Molecular Weight | 274.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Ketoglutaric Standards
- .alpha.-Ketoglutaric acid diethyl ester 5965-53-7 Diethyl 2-oxoglutarate Diethyl oxalpropionate Ethyl ethoxalylpropionate Glutaric acid, diethyl ester NSC-111179 NSC111179 Pentanedioic acid, diethyl ester (CAS 5965-53-7)
- 2-Ketoglutaric acid-d<SUB>6</SUB> (CAS 1173021-86-7)
- alpha-Ketoglutaric acid-[13C2,d2] (CAS 123953-28-6)
- 2-Ketoglutaric Acid-13C1 (CAS 108395-15-9)
- α-Ketoglutaric acid disodium salt dihydrate (CAS 1282616-74-3)
- α-KETOGLUTARIC ACID, DISODIUM SALT 13C4 (CAS 1429051-79-5)
- alpha-Ketoglutaric acid xsodium salt (CAS 17091-15-5)
- α-Ketoglutaric acid sodium salt (CAS 22202-68-2)
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