Enzalutamide Impurity 50 CAS CATO-C4X-101650
| CAS No. | CATO-C4X-101650 |
| Molecular Formula | C12H14FN3O4 |
| Molecular Weight | 283.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Enzalutamide Impurity 50 (C12H14FN3O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Enzalutamide Impurity 50 (CAS CATO-C4X-101650, C12H14FN3O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14FN3O4 |
| Molecular Weight | 283.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Enzalutamide Standards
- Enzalutamide Impurity 38 (CAS 948294-47-1)
- Enzalutamide Impurity N1 (CAS 2227589-23-1)
- Enzalutamide Impurity 67 (CAS CATO-C4X-101667)
- Enzalutamide Impurity 56 (CAS CATO-C4X-101656)
- Enzalutamide Impurity 61 (CAS CATO-C4X-101661)
- Enzalutamide Impurity 7 (CAS 1802242-47-2)
- Enzalutamide Impurity 45 (CAS 1332524-01-2)
- Enzalutamide Impurity 69 (CAS 2088914-58-1)
Recommended Standards
- N-(2-fluorophenyl)-6-(1H-1,2,4-triazol-1-yl)nicotinamide (CAS 672951-19-8)
- 4-Nitro Sulfamethoxazole (CAS 29699-89-6)
- Collagen (CAS 9064-67-9)
- Ethyl 2-(4-(difluoromethyl)-3,6-dimethyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate (CAS 1011380-61-2)
- Lacosamide Impurity 43 (CAS 69805-82-9)
- Lurbinectedin Impurity 35 (CAS CATO-C4X-311435)
- Hydrocortisone Impurity 59 (CAS CATO-C4X-140159)
- 3-amino-1-(2-aminoethyl)urea dihydrochloride (CAS 1311318-28-1)
- 3,4-dihydro-2H-1-benzopyran-4-ylmethanol (CAS 33313-82-5)
- 7-Chloro-2,5-dimethyl-[1,2,4]triazolo[1,5-c]pyrimidine (CAS 623158-28-1)
- 2-((3,4-Dimethylcyclohexyl)amino)-N,N-dimethylacetamide (CAS 1342347-81-2)
- Ethyl 12-aminododecanoate (CAS 53005-23-5)
- 4-(4-Methyl-2,5-dioxoimidazolidin-4-yl)benzoic acid (CAS 184763-33-5)
- Semaglutide Impurity 149 (CAS CATO-C4X-2226149)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com