Vardenafil Impurity 28 CAS CATO-C4X-101728
| CAS No. | CATO-C4X-101728 |
| Molecular Formula | C21H28N6O4S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Vardenafil Impurity 28 (C21H28N6O4SC2HF3O2) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Vardenafil Impurity 28 (CAS CATO-C4X-101728) is a certified pharmaceutical impurity reference standard with the molecular formula C21H28N6O4SC2HF3O2 and a molecular weight of 574.58 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Vardenafil Impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H28N6O4S C2HF3O2 |
| Molecular Weight | 574.58 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Vardenafil Standards
- Vardenafil Impurity 29 (CAS 1009013-42-6)
- Vardenafil-d5 (CAS 1189685-70-8)
- Vardenafil Hydrochloride Trihydrate EP Impurity C (CAS 1255919-03-9)
- Vardenafil Acetyl Analogue (CAS 1261351-28-3)
- Vardenafil Acetyl-d5 Analogue (CAS 1330171-51-1)
- Vardenafil Impurity 30 (CAS 1339092-18-0)
- Vardenafil Impurity 46 (CAS 1417529-59-9)
- Vardenafil Impurity 54 (CAS 1810028-99-9)
Recommended Standards
- Dosulepin EP Impurity E (CAS 25627-38-7)
- Bicyclic Chinese Pharmacopoeia Impurity 2 (CAS CATO-C4X-25553)
- Pimavanserin Impurity 39 (CAS CATO-C4X-193839)
- N,N-Dimethyl-1-(3-((methylamino)methyl)phenyl)methanamine dihydrochloride (CAS 1185149-23-8)
- Mercaptoacetic Acid (CAS 68-11-1)
- 5-(3-Chlorophenoxy)furan-2-carboxylic acid (CAS 1248668-43-0)
- 5,7-Difluoroquinoline-6-carboxylic acid (CAS 1398504-28-3)
- 3-Fluorobenzo[b]thiophene (CAS 1038780-99-2)
- tert-Butyl 2-(6-methyl-4,8-dioxo-1,3,6,2-dioxazaborocan-2-yl)-1H-pyrrole-1-carboxylate (CAS 1313759-37-3)
- Tirzepatide Impurity 21 X TFA Salt (CAS CATO-C4X-324021)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com