Vonoprazan Impurity 294 CAS CATO-C4X-1020294
| CAS No. | CATO-C4X-1020294 |
| Molecular Formula | C32H24F2N6O5S2 |
| Molecular Weight | 674.70 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Vonoprazan Impurity 294 (CAS CATO-C4X-1020294, C32H24F2N6O5S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Vonoprazan Impurity 294 (C32H24F2N6O5S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Vonoprazan Impurity 294 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C32H24F2N6O5S2 |
| Molecular Weight | 674.70 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 23.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 2 |
Related Vonoprazan Standards
- Vonoprazan Impurity 172 (CAS CATO-C4X-1020172)
- Vonoprazan Impurity 245 (CAS CATO-C4X-1020245)
- Vonoprazan Impurity 115 (CAS CATO-C4X-1020115)
- Vonoprazan Impurity 100 (CAS CATO-C4X-1020100)
- Vonoprazan Impurity 252 (CAS CATO-C4X-1020252)
- Vonoprazan Fumarate Impurity 118 (CAS CATO-C4X-1020118)
- Vonoprazan Impurity 275 (CAS CATO-C4X-1020275)
- Vonoprazan Impurity 116 (CAS CATO-C4X-1020116)
Recommended Standards
- N-Nitroso Cefoperazone 3 (CAS CATO-C4X-114954)
- Suc-Phe-Ala-Ala-Phe-pNA (CAS 110906-89-3)
- N-Nitroso Cefoperazone 1 (CAS CATO-C4X-114952)
- [DAla2,Hyp4,Tyr5] b-Casomorphin (1-5), amide (CAS 102029-98-1)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
- Levosimendan Impurity 21 (CAS 244077-42-7)
- Lornoxicam impurity 52 (CAS 906522-88-1)
- 4-cyanobutane-1-sulfonyl chloride (CAS 35517-25-0)
- n-(2-Hydroxyethyl)-2,5-dimethylbenzenesulfonamide (CAS 354992-40-8)
- 4'-(4-(Diphenylamino)phenyl)-5'-phenyl-[1,1':2',1''-terphenyl]-4-carbonitrile (CAS 2170282-57-0)
- ethyl 2-[5-(hydroxymethyl)benzofuran-3-yl]acetate (CAS 2623103-04-6)
- 2-Bromo-3-methyl-n-[3-(trifluoromethyl)phenyl]butanamide (CAS 391220-21-6)
- 4-(3-(Piperidin-1-ylmethyl)benzoyl)benzonitrile (CAS 898792-72-8)
- Neuropeptide GE (CAS 134748-04-2)
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