Carfilzomib Impurity 38 (Mixture of Diastereomers) CAS CATO-C4X-102238
| CAS No. | CATO-C4X-102238 |
| Molecular Formula | C46H65N5O14 |
| Molecular Weight | 912.03 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Carfilzomib Impurity 38 (Mixture of Diastereomers) (CAS CATO-C4X-102238), a pharmacopoeial impurity reference standard (molecular formula C46H65N5O14, MW 912.03 g/mol) used for the identification and quantification of trace impurities in APIs.
Carfilzomib Impurity 38 (Mixture of Diastereomers) (C46H65N5O14) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C46H65N5O14 |
| Molecular Weight | 912.03 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Carfilzomib Standards
- Carfilzomib Impurity 57 (CAS CATO-C4X-102257)
- Carfilzomib Impurity 60 (Mixture of Diastereomers) (CAS CATO-C4X-102260)
- Carfilzomib Impurity 40 (CAS CATO-C4X-102240)
- Carfilzomib Impurity 89 (CAS CATO-C4X-102289)
- Carfilzomib Impurity 93 (CAS CATO-C4X-102293)
- Carfilzomib Impurity 94 (CAS CATO-C4X-102294)
- Carfilzomib Impurity 64 (CAS 1541171-68-9)
- Carfilzomib Impurity 79 (CAS CATO-C4X-102279)
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