Capecitabine Impurity 53 CAS CATO-C4X-102453
| CAS No. | CATO-C4X-102453 |
| Molecular Formula | C21H28FN3O9 |
| Molecular Weight | 485.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Capecitabine Impurity 53 (C21H28FN3O9) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Capecitabine Impurity 53 (CAS CATO-C4X-102453, C21H28FN3O9) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Capecitabine Impurity 53 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H28FN3O9 |
| Molecular Weight | 485.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Capecitabine Standards
- Capecitabine Impurity 38 (CAS CATO-C4X-102438)
- Capecitabine Impurity 40 (CAS CATO-C4X-102440)
- Capecitabine Impurity 54 (CAS CATO-C4X-102454)
- Capecitabine Impurity 17 (CAS 1262133-68-5)
- Capecitabine Impurity 24 (CAS CATO-C4X-102424)
- Capecitabine Impurity 8 (CAS 1262133-66-3)
- Capecitabine Impurity 9 (CAS 1262133-64-1)
- Capecitabine Impurity 22 (CAS CATO-C4X-102422)
Recommended Standards
- 4-Nitrophenyl 2-3-4-6-tetra-O-acetyl-β-D-thiogalactopyranoside (CAS 41341-55-3)
- Naphthalen-2-yl N-(phenylsulfonyl)-N-(3-(trifluoromethyl)phenyl)glycinate (CAS 343373-96-6)
- Cariprazine Impurity 60 (CAS CATO-C4X-240860)
- 4-Nitrophenyl 3-O-benzoyl-4-6-cyclohexylidene-β-D-mannopyranoside (CAS 102717-17-9)
- Enarodustat Impurity 19 (CAS CATO-C4X-322819)
- Pyronaridine Impurity 15 (CAS CATO-C4X-297815)
- Pimecrolimus Impurity 22 (CAS 137712-89-1)
- N-(4-(4-benzylpiperazin-1-yl)phenyl)-2-chloroacetamide (CAS 923770-75-6)
- Methyl 2,4,6-trichloropyrimidine-5-carboxylate (CAS 87846-94-4)
- 5-Bromo-3-(p-tolyl)isoxazole (CAS 51725-95-2)
- Potassium 2,2'-((2-(2-(2-(bis(carboxylatomethyl)amino)-5-(2,7-dichloro-6-oxido-3-oxo-3H-xanthen-9-yl)phenoxy)ethoxy)-4-methylphenyl)azanediyl)diacetate (CAS 853400-67-6)
- 2-methyl-1H,2H,3H,4H-pyrido[3,4-b]pyrazin-3-one hydrochloride (CAS 1432677-78-5)
- Dalbavancin Impurity 20 (CAS CATO-C4X-160220)
- Peptide 74 (H-8545.0500) (CAS 132116-39-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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