Mirabegron Impurity 77 DiHCl CAS CATO-C4X-103277
| CAS No. | CATO-C4X-103277 |
| Molecular Formula | C21H24N4O2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Mirabegron Impurity 77 DiHCl (CAS CATO-C4X-103277, C21H24N4O2SHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Mirabegron Impurity 77 DiHCl (C21H24N4O2SHCl) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H24N4O2S 2*HCl |
| Molecular Weight | 432.97 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Mirabegron Standards
- Mirabegron Impurity 73 (CAS 100-12-9)
- Mirabegron Impurity 40 (CAS 1154949-80-0)
- rac-Mirabegron-d5 (CAS 1215807-38-7)
- Mirabegron Impurity 147 (CAS 1310279-36-7)
- Mirabegron Impurity 32 (CAS 1310279-36-7 (free base))
- Mirabegron N-t-BOC Impurity (CAS 1329485-55-3)
- Mirabegron Impurity 139 (CAS 1330277-46-7)
- Mirabegron Impurity 62 (CAS 135365-07-0)
Recommended Standards
- Nitrendipine impurity 20 (CAS CATO-C4X-183420)
- R-Cefadroxil Sulfoxide (CAS CATO-C4X-122415)
- Gatifloxacin Impurity 23 (CAS 112811-58-2)
- 6-Chloro-1-(4-chlorobenzyl)-1H-indazol-3(2H)-one (CAS 103427-60-7)
- 7-Methyl-4-oxo-4h-pyrido[1,2-a]pyrimidine-3-carboxylic acid (CAS 33359-68-1)
- 3-(1-Methyl-5-oxo-pyrrolidin-3-yl)-3-oxo-propionic acid methyl ester (CAS 1083282-29-4)
- 3-Butyn-1-amine Hydrochloride (CAS 88211-50-1)
- 3-(6-Bromo-2-oxopyrrolo[4,3,2-de]quinolin-1(2H)-yl)piperidine-2,6-dione (CAS 2767588-39-4)
- Isopropyl 2-((4-amino-5-(4-chlorophenyl)-4H-1,2,4-triazol-3-yl)thio)acetate (CAS 577789-92-5)
- Neuropeptide Y (13-36) (porcine) (CAS 113662-54-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com