Donepezil Impurity 19 CAS CATO-C4X-103919
| CAS No. | CATO-C4X-103919 |
| Molecular Formula | C17H25NO3 |
| Molecular Weight | 291.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Donepezil Impurity 19.
Donepezil Impurity 19 (CAS CATO-C4X-103919) is a certified pharmaceutical impurity reference standard with the molecular formula C17H25NO3 and a molecular weight of 291.39 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Donepezil Impurity 19 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 291.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H25NO3 |
| Molecular Weight | 291.39 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Donepezil Standards
- Donepezil EP impurity A (CAS 120014-30-4)
- Donepezil Impurity 75 (CAS CATO-C4X-103975)
- Donepezil Impurity 33 (E/Z Mixture) (CAS 149874-91-9)
- Donepezil impurity 01 (CAS 2452407-68-8)
- Donepezil Impurity 30 (CAS CATO-C4X-103930)
- Donepezil Impurity 39 (CAS 923571-15-7)
- Donepezil Impurity 54 (CAS CATO-C4X-103954)
- Donepezil Alkene Pyridine N-Oxide (CAS 896134-07-9)
Recommended Standards
- Bunolol (CAS 27591-01-1)
- Pregabalin Impurity 138 (CAS 930585-94-7)
- 951886-07-0 Ethyl 5-[4-(N,N-Diethylamino)phenyl]-5-oxovalerate MFCD09801910 (CAS 951886-07-0)
- Dapoxetine Impurity 26 (CAS 147199-39-1)
- Azelastine Impurity 70 (CAS CATO-C4X-139670)
- AZD-9291 Impurity 16 (CAS 65843-60-9)
- Roflumilast Impurity 59 (CAS CATO-C4X-193559)
- 3,3-Dimethyl-11-(3-phenoxyphenyl)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one (CAS 300689-13-8)
- N-[(E)-2-[3-(Benzylsulfanyl)-6-methyl-1,2,4-triazin-5-yl]ethenyl]-4-fluoroaniline (CAS 477866-51-6)
- 2-[(Dimethylamino)methylidene]cycloheptane-1,3-dione (CAS 499206-24-5)
- (8-Syn)-N,N-dimethyl-3-azabicyclo[3.2.1]octan-8-amine dihydrochloride (CAS 1609403-46-4)
- N-(5-benzylthiazol-2-yl)-2-chloroacetamide (CAS 301306-13-8)
- (9S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-9-isopropyl-12-methoxy-5,5,10-trimethyl-3,6,8-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid (CAS 1438851-55-8)
- Semaglutide impurity 215 (CAS CATO-C4X-2226215)
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