Ceritinib Impurity 7 CAS CATO-C4X-10487
| CAS No. | CATO-C4X-10487 |
| Molecular Formula | C13H13Cl2N3OS |
| Molecular Weight | 330.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Ceritinib Impurity 7 (CAS CATO-C4X-10487) is a certified pharmaceutical impurity reference standard with the molecular formula C13H13Cl2N3OS and a molecular weight of 330.23 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, Ceritinib Impurity 7 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 330.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C13H13Cl2N3OS |
| Molecular Weight | 330.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Ceritinib Standards
- Ceritinib Impurity 85 (CAS 761440-17-9)
- Ceritinib Impurity 1 (CAS CATO-C4X-10481)
- Ceritinib Impurity 83 (CAS CATO-C4X-104883)
- Ceritinib Impurity 33 (CAS CATO-C4X-104833)
- Ceritinib Impurity 17 (CAS CATO-C4X-104817)
- Ceritinib Impurity 57 (CAS CATO-C4X-104857)
- Ceritinib Impurity 18 (CAS CATO-C4X-1048918)
- Ceritinib Impurity 13 (CAS CATO-C4X-104813)
Recommended Standards
- 3,5-bis(trifluoromethyl)phenyl benzimidazole (CAS 1280585-62-7)
- [(4-bromo-2-fluorophenyl)methyl][2-(4-methylpiperazin-1-yl)ethyl]amine (CAS 1183009-18-8)
- Propyl 2-amino-4-(3,4-dichlorophenyl)thiophene-3-carboxylate (CAS 351156-80-4)
- 4-(4'-Bromo-[1,1'-biphenyl]-4-yl)-2-methylthiazole (CAS 1421262-90-9)
- Dicloxacillin Impurity 8 (CAS CATO-C4X-16158)
- Azithromycin EP Impurity B (CAS 307974-61-4)
- Nortriptyline EP Impurity F-d3 HCl (CAS 342611-00-1)
- 3,4-Dimethyl-1,2,5-thiadiazole (CAS 5728-21-2)
- Ala-Ala-Phe p-nitroanilide (CAS 61043-41-2)
- 2-Aminopyrimidine-5-methanol (CAS 120747-85-5)
- 2-(1-Methyl-2-oxoindolin-3-yl)acetic acid (CAS 21591-75-3)
- 4-Butylthiomorpholine-3-carboxylic acid (CAS 1544096-39-0)
- 4-(1-Methyl-1H-pyrrol-2-yl)but-3-yn-2-one (CAS 144912-18-5)
- Vialox Peptide(Pentapeptide-3) (CAS 135679-88-8)
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