Vortioxetine Impurity 137 CAS CATO-C4X-1056137
| CAS No. | CATO-C4X-1056137 |
| Molecular Formula | C18H21ClN2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Vortioxetine Impurity 137 (CAS CATO-C4X-1056137, C18H21ClN2SHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution, Vortioxetine Impurity 137 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 369.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H21ClN2S HCl |
| Molecular Weight | 369.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Vortioxetine Standards
- Vortioxetine Impurity 63 (CAS 1009-85-4)
- Vortioxetine Impurity 2 (CAS 1011-13-8)
- Vortioxetine Impurity 89 (CAS 1019453-85-0)
- Vortioxetine Impurity 116 (CAS 102439-46-3)
- Vortioxetine Impurity 88 (CAS 103-19-5)
- Vortioxetine Impurity 60 (CAS 1049755-55-6)
- Vortioxetine Impurity 48 (CAS 105456-67-5)
- Vortioxetine Impurity 101 (CAS 107832-66-6)
Recommended Standards
- Roxatidine Impurity 66 (CAS 2765350-63-6)
- Vonoprazan Impurity 155 (CAS 403710-57-6)
- Azilsartan Impurity 22 (CAS CATO-C4X-109622)
- 4-(3-Methoxyphenyl)-3-hexanone (CAS 7355-84-2)
- 2-Amino-4-chloro-3-methoxybenzoic acid (CAS 67303-46-2)
- Pretomanid Impurity 17 (CAS CATO-C4X-260617)
- 2-(2-Chloro-4-fluorophenoxy)propanohydrazide 588677-35-4 6184AE C9H10ClFN2O2 (CAS 588677-35-4)
- 6-Isopropoxybenzo[d][1,3]dioxol-5-amine (CAS 1312698-41-1)
- 8-Ethoxyquinolin-5-ol (CAS 856083-19-7)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
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