Vortioxetine Impurity 17 TFA CAS CATO-C4X-105617
| CAS No. | CATO-C4X-105617 |
| Molecular Formula | C18H21ClN2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Vortioxetine Impurity 17 TFA (CAS CATO-C4X-105617, C18H21ClN2SC2HF3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Vortioxetine Impurity 17 TFA (C18H21ClN2SC2HF3O2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Vortioxetine Impurity 17 TFA meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H21ClN2S C2HF3O2 |
| Molecular Weight | 446.91 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Vortioxetine Standards
- Vortioxetine Impurity 63 (CAS 1009-85-4)
- Vortioxetine Impurity 2 (CAS 1011-13-8)
- Vortioxetine Impurity 89 (CAS 1019453-85-0)
- Vortioxetine Impurity 116 (CAS 102439-46-3)
- Vortioxetine Impurity 88 (CAS 103-19-5)
- Vortioxetine Impurity 60 (CAS 1049755-55-6)
- Vortioxetine Impurity 48 (CAS 105456-67-5)
- Vortioxetine Impurity 101 (CAS 107832-66-6)
Recommended Standards
- Loxoprofen Impurity 161 (CAS CATO-C4X-1488161)
- Xanomeline impurity 21 (CAS CATO-C4X-330121)
- Avatrombopag impurity 123 (CAS CATO-C4X-2234123)
- trans-3-(Methylthio)cyclobutanamine Hydrochloride (CAS 2059915-02-3)
- 2-(Cyclopentylamino)-1-(4-fluorophenyl)ethan-1-one (CAS 1225621-33-9)
- N-(4-(tert-butyl)phenyl)-2-oxo-1-(4-(trifluoromethyl)benzyl)-1,2-dihydropyridine-3-carboxamide (CAS 338977-42-7)
- 1-(2-Ethoxyphenyl)-1h-imidazole-2-thiol (CAS 1152533-49-7)
- 6-Bromo-3-(2-isopropylphenyl)-[1,2,4]triazolo[4,3-a]pyridine (CAS 876301-26-7)
- n-(3-Ethynylphenyl)-4-methylbenzenesulfonamide (CAS 860788-60-9)
- Semaglutide Impurity 8 (CAS CATO-C4X-22268)
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