Vortioxetine Impurity 57 CAS CATO-C4X-105657
| CAS No. | CATO-C4X-105657 |
| Molecular Formula | C18H21ClN2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Vortioxetine Impurity 57 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Vortioxetine Impurity 57 (CAS CATO-C4X-105657), a pharmacopoeial impurity reference standard (molecular formula C18H21ClN2SHBr, MW 413.80 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Vortioxetine Impurity 57 (C18H21ClN2SHBr) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 413.80 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H21ClN2S HBr |
| Molecular Weight | 413.80 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Vortioxetine Standards
- Vortioxetine Impurity 63 (CAS 1009-85-4)
- Vortioxetine Impurity 2 (CAS 1011-13-8)
- Vortioxetine Impurity 89 (CAS 1019453-85-0)
- Vortioxetine Impurity 116 (CAS 102439-46-3)
- Vortioxetine Impurity 88 (CAS 103-19-5)
- Vortioxetine Impurity 60 (CAS 1049755-55-6)
- Vortioxetine Impurity 48 (CAS 105456-67-5)
- Vortioxetine Impurity 101 (CAS 107832-66-6)
Recommended Standards
- Isavuconazole Impurity 44 (CAS CATO-C4X-123644)
- Norethisterone Acetate EP Impurity D (CAS CATO-C4X-171316)
- Lenalidomide Impurity 8 (CAS 2197414-55-2)
- 63148-57-2 Poly(methylhydrosiloxane) Siloxanes and Silicones, Me hydrogen Polymethylhydrogensiloxane, trimethylsiloxy end blocked Siloxanes and silicones, methyl hydrogen (CAS 63148-57-2)
- 1-(4-bromobenzyl)-N,5-dimethyl-1H-1,2,3-triazole-4-carboxamide (CAS 952182-54-6)
- 2-(5-Methyl-3-oxo-2-(p-tolyl)-2,3-dihydro-1H-pyrazol-4-yl)acetic acid (CAS 1015844-46-8)
- Carfilzomib Impurity 34 (CAS 247068-81-1)
- Risperidone impurity 01 (CAS 146801-00-5)
- 3-((3-Chlorobenzyl)oxy)propane-1-sulfonyl chloride (CAS 1463435-85-9)
- D-Tyr1-Tirzepatide (CAS CATO-CPTD788928)
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