Ibrutinib Impurity 107 CAS CATO-C4X-1064107
| CAS No. | CATO-C4X-1064107 |
| Molecular Formula | C20H20N4O2 |
| Molecular Weight | 348.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ibrutinib Impurity 107 (C20H20N4O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Ibrutinib Impurity 107 (CAS CATO-C4X-1064107) is a certified pharmaceutical impurity reference standard with the molecular formula C20H20N4O2 and a molecular weight of 348.40 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ibrutinib Impurity 107 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H20N4O2 |
| Molecular Weight | 348.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Ibrutinib Standards
- Ibrutinib Impurity 42 (CAS CATO-C4X-106442)
- Ibrutinib Impurity 109 (CAS 2803461-05-2)
- Ibrutinib Impurity 144 (CAS CATO-C4X-1064144)
- Ibrutinib Impurity 152 (CAS CATO-C4X-1064152)
- Ibrutinib Impurity 153 (CAS CATO-C4X-1064153)
- Ibrutinib Impurity 159 (CAS CATO-C4X-1064159)
- Ibrutinib Impurity 116 (CAS 1807619-68-6)
- Ibrutinib Impurity 157 (CAS CATO-C4X-1064157)
Recommended Standards
- Milnacipran impurity 25 (CAS 2386090-46-4)
- Rosuvastatin Impurity 192 (CAS 1092844-00-2)
- Tetra(cyanoethoxymethyl) methane (CAS 2465-91-0)
- Cefaclor Impurity 21 (CAS CATO-C4X-127021)
- Lacosamide EP Impurity D (CAS 262845-82-9)
- N-Nitroso N-Devaleryl Valsartan Methyl Ester Impurity 89 (mixture of isomers) (CAS CATO-C4X-105789)
- Naloxone Hydrochloride EP Impurity B (CAS 1352085-46-1)
- 3-bromo-1-methyl-1H,6H,7H-pyrrolo[2,3-c]pyridin-7-one (CAS 1375474-44-4)
- 2-Methyl-1-(2,2,2-trifluoroacetyl)pyrrolidine-3-carboxylic acid (CAS 1508488-17-2)
- 7-Fluoro-1H-pyrrolo[2,3-c]pyridine-2-carbaldehyde (CAS 2231673-53-1)
- N-[1-(2H-1,3-benzodioxol-5-yl)ethyl]hydroxylamine (CAS 904813-15-6)
- N-Hydroxy-N-(3-(3-phenoxyphenyl)allyl)acetamide (CAS 106328-57-8)
- N-(3-fluorophenyl)-2-((5-(furan-2-yl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 557067-86-4)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
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