Empagliflozin impurity 191 CAS CATO-C4X-1065191
| CAS No. | CATO-C4X-1065191 |
| Molecular Formula | C34H32Cl2O4 |
| Molecular Weight | 575.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Empagliflozin impurity 191 (C34H32Cl2O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a process- or degradation-related impurity, Empagliflozin impurity 191 (CAS CATO-C4X-1065191, C34H32Cl2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C34H32Cl2O4 |
| Molecular Weight | 575.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 11 (CAS CATO-C4X-106511)
- Empagliflozin impurity 221 (CAS CATO-C4X-1065221)
- Empagliflozin impurity 318 (CAS CATO-C4X-1065318)
- Empagliflozin Impurity 74 (CAS 81058-27-7)
- Empagliflozin Impurity N7 (CAS 872980-38-6)
- Empagliflozin impurity 316 (CAS CATO-C4X-1065316)
- Empagliflozin Impurity 124 (CAS CATO-C4X-1065124)
- Empagliflozin Impurity 87 (CAS CATO-C4X-1065287)
Recommended Standards
- tert-Butyl (3R,5R,6S)-3-allyl-2-oxo-5,6-diphenyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butyl)morpholine-4-carboxylate (CAS 1345672-86-7)
- Trifluoromethylsulfonatotricarbonyl(2,2'-bipyridine)rhenium(I) (CAS 97170-94-0)
- 80907-56-8 Tris(2,2'-bipyrazine)ruthenium(II) hexafluorophosphate, 95% MFCD27952557 (CAS 80907-56-8)
- Mioflazine (CAS 79467-23-5)
- Roxadustat Impurity 33 (CAS 1455091-04-9)
- Olaparib Impurity 73 (CAS 868-85-9)
- Efavirenz Impurity 11 (CAS CATO-C4X-162711)
- 2-Methylpropane-2-sulfinic acid (CAS 29099-08-9)
- 4-(2-(Benzo[d][1,3]dioxol-5-yl)vinyl)quinoline (CAS 3253-51-8)
- 5-(Benzo[d]thiazol-2-yl)pyridin-2-ol (CAS 54628-01-2)
- Caffeic Acid-13C3 (CAS 1185245-82-2)
- (E)-2-(2-(4,4-Difluorocyclohexyl)vinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2412762-77-5)
- 4-{5-[(Cyclobutylcarbonyl)amino]-pyridin-2-yl}benzoic acid (CAS 1170357-94-4)
- Neuropeptide Y (18-36) (CAS 114495-97-5)
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