Ibuprofen impurity 143 CAS CATO-C4X-1082143

Description

The occurrence of Ibuprofen impurity 143 is closely related to a flavonoid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Ibuprofen impurity 143 (CAS CATO-C4X-1082143), a pharmacopoeial impurity reference standard (molecular formula C19H26O5, MW 334.41 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a flavonoid core, a hydroxyl group, an ether linkage, Ibuprofen impurity 143 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 334.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Ibuprofen impurity 143 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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