Felodipine Impurity 34 CAS CATO-C4X-109434
| CAS No. | CATO-C4X-109434 |
| Molecular Formula | C12H10Cl2O3 |
| Molecular Weight | 273.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 273.11 g/mol gives Felodipine Impurity 34 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Felodipine Impurity 34 (CAS CATO-C4X-109434) is a certified pharmaceutical impurity reference standard with the molecular formula C12H10Cl2O3 and a molecular weight of 273.11 g/mol.
The molecular framework of Felodipine Impurity 34 (C12H10Cl2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Felodipine Impurity 34 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10Cl2O3 |
| Molecular Weight | 273.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Felodipine Standards
- Felodipine Impurity 1 (CAS 68064-69-7)
- Felodipine Impurity 12 (CAS 74073-22-6)
- Felodipine Impurity 25(E/Z Mixture) (CAS 313967-20-3)
- Felodipine Impurity 33 (CAS CATO-C4X-109433)
- Felodipine Impurity 35 (CAS CATO-C4X-109435)
- Felodipine Impurity 36 (CAS CATO-C4X-109436)
- Felodipine Impurity 39 (CAS CATO-C4X-109439)
- Felodipine Impurity 38 (CAS CATO-C4X-109438)
Recommended Standards
- Methyl 2-[4-(2-bromoethoxy)phenyl]acetate (CAS 100125-95-9)
- N-(5-bromothiazol-2-yl)furan-2-carboxamide (CAS 90001-39-1)
- Ethyl 2-(3-bromo-4-methoxyphenyl)acetate (CAS 100125-96-0)
- N-(3-Iodobenzyl)cyclopropanamine (CAS 856252-59-0)
- Cefaclor Impurity 55 (CAS CATO-C4X-127055)
- Bambuterol Impurity 11 (CAS CATO-C4X-274611)
- Rifapentine impurity 24 (CAS CATO-C4X-195924)
- (E)-oct-3-en-2-ol (CAS 57648-55-2)
- propan-2-yl 2-[2-(aminomethyl)-1,3-thiazol-4-yl]acetate (CAS 1427380-81-1)
- 2-Hydrazono-4-nitro-2,3-dihydro-1H-benzo[d]imidazole (CAS 99122-16-4)
- Tetrahydropyran-4-carboxamidine Hydrochloride (CAS 426828-34-4)
- 3-Phenyl-1-(quinoxalin-2-yl)propan-1-amine (CAS 885275-30-9)
- 7-(Diethylamino)-3-((4-ethylphenyl)sulfonyl)-6-fluoro-1-propylquinolin-4(1H)-one (CAS 892770-39-7)
- Semaglutide impurity 33 (CAS CATO-C4X-222633)
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