Azilsartan Impurity 166 CAS CATO-C4X-1096166

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-1096166
Molecular FormulaC27H23N5O6
Molecular Weight513.50 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Azilsartan Impurity 166 CAS CATO-C4X-1096166 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 513.50 g/mol gives Azilsartan Impurity 166 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Azilsartan Impurity 166 (CAS CATO-C4X-1096166) is a certified pharmaceutical impurity reference standard with the molecular formula C27H23N5O6 and a molecular weight of 513.50 g/mol.

Azilsartan Impurity 166 (C27H23N5O6) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC27H23N5O6
Molecular Weight513.50 g/mol
AppearancePale yellow to yellow crystalline powder
Purity≥95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)19.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms5

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