Ezetimibe Impurity 136 CAS CATO-C4X-1098136

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-1098136
Molecular FormulaC39H46F2N2O5Si2
Molecular Weight716.96 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ezetimibe Impurity 136 CAS CATO-C4X-1098136 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 716.96 g/mol gives Ezetimibe Impurity 136 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Ezetimibe Impurity 136 (CAS CATO-C4X-1098136) is a certified pharmaceutical impurity reference standard with the molecular formula C39H46F2N2O5Si2 and a molecular weight of 716.96 g/mol.

Ezetimibe Impurity 136 (C39H46F2N2O5Si2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Ezetimibe Impurity 136 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC39H46F2N2O5Si2
Molecular Weight716.96 g/mol
Purity≥95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)17.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentF-containing
Nitrogen Atoms2

Related Ezetimibe Standards

Recommended Standards

Why CATO?